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Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

Dexmedetomidine vs remifentanil for reduction of postoperative agitation

Postoperative agitation is a common anaesthetic complication in children with a significant impact to care and outcomes. The authors studied preschool children to compare the effect of intravenous administration of dexmedetomidine and remifentanil on postoperative agitation following strabismus surgery under...

Blinking blepharitis has a lot to answer for…

Never ignore the small things’…someone once said. There is no doubt blepharitis is one of the most common eye conditions encountered daily, but with the typical pressures of a busy outpatient department, the management of more obvious, sight-threatening conditions necessarily...

Implantation of diffractive trifocal intraocular lens

This study reports on 60 eyes of 120 patients who underwent routine cataract surgery followed by implantation of the trifocal IOL model Lisa tri-839MP. This is a diffractive trifocal preloaded IOL with no interruption at the haptic-optic junction, 360 degrees...

How to diagnose and treat Acanthamoeba keratitis

Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...

Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease

In recent years artificial tear drops addressing tear film osmolarity have come onto the market. Increased tear evaporation and reduced tear volume results in tear hyperosmolarity. This triggers an inflammatory process leading to apoptosis of goblet and epithelial cells. Trehalose,...

Gemini Untwined: treating craniopagus conjoined twins

The authors discuss the successful separation of craniopagus conjoined twins at Great Ormond Street Hospital and the role of the ophthalmologist in such cases. Craniopagus conjoined twins are extraordinarily rare, occurring in only one in 2.5 million births and representing...

Survey of paediatric ophthalmology practice in the US

The purpose of this study was to develop a survey to assess possible solutions for an economic turnaround in paediatric ophthalmology. A 12-item survey was circulated with questions related to practice location, setting and years in practice. Responses were received...

Orbis achieves WHO trachoma elimination threshold in Sheka Zone, Southwest Ethiopia

Ahead of World Neglected Tropical Diseases (NTD) Day on 30 January, international eye care charity Orbis has announced that it has achieved the World Health Organisation (WHO) threshold for eliminating trachoma as a public health concern in Sheka Zone, Southwest...

Selective laser trabeculoplasty after medical treatment

Selective laser trabeculoplasty (SLT) is a well-established treatment for open-angle glaucoma (OAG) and ocular hypertension (OHT). This post-hoc secondary analysis of the LiGHT trial extension examined SLT as a secondary intervention after 3 years of protocolised medical therapy in patients...

100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

Retinotopic fMRI reveals visual dysfunction and functional reorganisation in the visual cortex of glaucoma patients

This study investigated the retinotopic functional representation in the visual cortex of mild to moderate primary open-angle glaucoma (POAG) participants and age-matched normal volunteers, using wide-view visual presentation, high-resolution retinotopic stimuli, and high-resolution blood oxygenation level dependent (BOLD) functional magnetic...