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New solutions in the prevention and treatment of Acanthamoeba keratitis

The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. News headlines detailing horror...

A unique case of macular burn from ‘toy’ laser

The first laser was created in 1960 and its name is an acronym for ‘light amplification by stimulated emission of radiation’. Laser technology has been used for medical, industrial, research and entertainment purposes in a variety of fields following extensive...

Cornea teaching techniques: one cornea donor tissue for two purposes

There is a national shortage in the UK in corneal graft material [1,2]. The majority (69%) of corneal transplants in the UK are partial thickness, with 35% being Descemet membrane endothelial keratoplasty (DMEK) [2]. During the preparation of the donor...

Ocular mucous membrane pemphigoid: the importance of early detection and treatment

Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterised by subepithelial bullae. The ocular manifestation of MMP, ocular mucous membrane pemphigoid (OMMP), is a sight-threatening condition characterised by conjunctival cicatricial changes associated with corneal vascularisation and scarring....

Apr/May 2014 Quiz 1

History A 45-year-old man presents with left-sided epiphora. During a dacrocystorhinostomy (DCR), the wall of the lacrimal sac was noted to be bulky. The sac wall is biopsied and sent for routine histopathology examination. The pathologist notes a distinctive feature...

Periocular burns: a literature review of classification, management protocols and outcomes of treatment

The author provides a review of the current literature regarding the principles of classification, management protocols of acute ocular and periocular burns and the role of the burn and oculoplastic surgeon involved in their care. More than two-thirds of facial...

My experience of the transition into a specialist orthoptist role

Michelle Dent discusses the process of transitioning into a new role and the pros and cons along the way. An opportunity arose for a permanent, full time, band 7 specialist role in the medical retina (MR) team in the Newcastle...

Diabetic Macular Oedema

Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...

Discussing treatment modalities for bilateral wet AMD

A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

Traumatic injuries from foam Nerf bullets

Background Three patients are presented in this case report: an adult and two children which were subjected to ocular injuries from Nerf gun bullets. Generally, Nerf guns are considered safer than airsoft guns. While there are many papers on airsoft...

Feb/Mar 2015 Quiz 2

History A 60-year-old white Caucasian male, with a history of acne, presented with slate grey pigmentation of his upper forehead, pre-auricular skin, peri-oral area, forearms and shins. The conjunctivae showed bilateral lower tarsal conjunctival multiple black dots. One of these...

Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD

This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...