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  • A novel parameter for angle closure

A novel parameter for angle closure
Reviewed by Jonathan Chan

4 February 2025 | Jonathan Chan | EYE - Glaucoma
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This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA), defined as the circumferential contact area between the pigmented iris epithelium and anterior lens surface. Gonioscpic angle closure (GAC) was defined as non-availability of the posterior trabecular meshwork in two or more angle quadrants. The mean age of patients was 62 years and 65.5% were female. Of 464 patients, 143 (28.6%) had GAC. Iridolenticular contact area was significantly associated with anterior chamber width, pupillary diameter, and iris curvature. The ILCA was smaller in eyes with GAC compared with those with open angle. And ILCA was independently associated with GCA, iridolenticular index, or angle opening distance. The authors concluded that ILCA is a significant predictor of angle closure independent of other biometric factors, it also represents a biometric risk factor in eyes with angle closure.

Investigating the determinants of iridolenticular contact area: a novel parameter for angle closure.
Tun TA, Nongpiur ME, Xu BY, et al.
BRITISH JOURNAL OF OPHTHALMOLOGY
2024;108:940–5.
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CONTRIBUTOR
Jonathan Chan

Royal Hallamshire Hospital, Sheffield, UK.

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