You searched for "infection"
Infections related to strabismus surgery
This review considers the range of infections occurring with strabismus surgery. Extraocular infections include conjunctiva, sub Tenon’s abscess and orbital cellulitis. Intraocular infection includes endophthalmitis. Prevention of infection and risk factors includes the issue of scleral penetration and use of...
Effect of syringe-filling technique and risk for endophthalmitis after intravitreal injection of anti-VEGF agents
2 August 2022
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Aflibercept, Anti-vascular endothelial growth factor, Bevacizumab, Endophthalmitis, Filling, Prefilled syringe, Ranibizumab, Syringe
In this retrospective study the authors compare the risk for post-injection endophthalmitis between different anti-vascular endothelial growth factor (VEGF) agents and syringe preparation technique. This multicentre study included 197,402 injections. The drugs included in this study were three Anti-VEGF agents...
Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service
3 April 2023
| Yasir Khan, Robin Hamilton, Adam Mapani, Catey Bunce, Ranjan Rajendram, Carlos Pavesio
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EYE - General
Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...
Running a high-volume nurse led intravitreal service using the Sp.eye device – the Stanley Eye Unit experience
2 February 2024
| Julia Baxter, Eoin Guerin, Catrin Bertalot, Alison Birch, Tracy Turner, Karen Evans
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EYE - Vitreo-Retinal
Introduction The vast majority of ophthalmology units utilise allied healthcare professionals (AHPs) to deliver intravitreal injections (IVIs). The Royal College of Ophthalmologists issued a statement 10 years ago advocating the use of non-medical practitioners performing IVIs [1]. The main benefit...
Systemic fungal infections and corneal transplants
This prospective study looked at corneal donors with positive medical history of systemic fungal infection (oral thrush or respiratory, urine, wound, sputum, bronchial, tracheal, or throat culture positive for fungus), to establish if the risk of post-keratoplasty fungal eye infections...
Antibiotic prophylaxis after intravitreal injections
1 June 2014
| Brian Ang
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EYE - General
The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...
Silent keratitis in failed graft
This study examined rates of asymptomatic keratitis in failed full thickness corneal grafts, which were not picked up clinically preoperatively. During a five year period 53 penetrating keratoplasties (PK) were performed for long-standing graft decompensation with stromal opacity and /...Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device
1 December 2021
| Ibrar Ahmed, Panayiotis Maghsoudlou, Hani Hasan, Allaaeldin Abumattar, Nimish Shah
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EYE - Vitreo-Retinal, EYE - General
Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...
Intravitreal injections delivered by ophthalmic clinical nurse specialists
1 June 2015
| Rita McLauchlan, D Armstrong, Konstantinos Balaskas, Sajjad Mahmood
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EYE - Vitreo-Retinal
Intravitreal injections of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab, for the treatment of wet age-related macular degeneration (AMD) was approved by National Institute for Health & Care Excellence (NICE) in 2008 [1]. The Manchester Royal Eye Hospital (MREH),...
Culture positivity of needles for IVT injections
1 December 2013
| Saruban Pasu
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EYE - Vitreo-Retinal
Given the worldwide use of intravitreal (IVT) injections, the authors of this paper set out to evaluate the rate of culture positivity of the needles used in routine IVT injections and compare this positivity between 27-gauge and 30-gauge needle tips....
The role of injection assistant devices in establishing a nurse-led AMD service
1 April 2018
| Hani Hasan
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EYE - Vitreo-Retinal
The author shares his experience of setting up a nurse-led service to deliver anti-VEGF intravitreal injections and how injection assistant devices supported training. Age-related macular degeneration (AMD) has become a leading cause of irreversible blindness [1]. It is estimated that...
Treatment of diabetic macular edema in vitrectomised eyes – comparison of intravitreal dexamethasone implant and posterior subtenon triamcinolone injection
3 April 2023
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Dexamethasone implant, Diabetic macular edema, Pars plana vitrectomy, Posterior subtenon triamcinolone
This retrospective study was aimed to compare intravitreal dexamethasone implant and posterior subtenon triamcinolone injection (PSTA) in the treatment of diabetic macular edema (DME) in vitrectomised eyes. Sixty-four (48.12%) patients who had received PSTA and 69 (51.88%) patients who had...
