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Retinal ganglion cell loss in diabetes and diabetic retinopathy
The aim of this observational case control study was to evaluate the association of diabetes and diabetic retinopathy (DR) with retinal ganglion cell loss. Cases were Chinese patients with type 2 diabetes with and without DR, aged 40-80 years. Eligible...
OVD influences
This prospective case series provides data on a previously uninvestigated area. Eyes due to have routine phakoemulsification were divided into six groups according to ophthalmic viscosurgical device (OVD) type. After cataract extraction aphasic refraction using intraoperative aberrometry with the ocular...
Case report of Leber hereditary optic neuropathy (LHON)
This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...
PlusoptiX and SPOT screening
The goal of this study was to determine whether an instrument that uses referral criteria having a high specificity (plusoptiX S08) would fail to refer children who have significant amblyopia and who would have been detected by an instrument using...
Dog bite lid lacerations
The characteristics of dog bite induced lid trauma are described in a large cohort of paediatric patients and the success rate of early repair of lacerations involving the lacrimal system. This is a retrospective review of 438 patients: 73 with...
Long-term esotropia and exotropia alignment
The authors review surgical outcomes for 317 children having surgery for esotropia (n=235) or exotropia (n=82) for comparative analysis using survival curves. Esotropia surgery was undertaken at a mean of 42 months; exotropia surgery at a mean of 60 months...
Propranolol treatment of infantile haemangioma
This is a retrospective review of 104 patients treated for infantile haemangioma between January 2009 and July 2012. All patients underwent pretesting either with protocol A (administration of test dose with routine observations) or protocol B (cardiology clinic assessment, including...
Combined ranibizumab and ablative therapy for Coat’s disease
The aim of this study was to observe the efficacy of intravitreal ranibizumab (IVR) combined with laser photocoagulation or cryotherapy, for Coats’ disease. Patients younger than 16 years of age who were diagnosed with Coats’ disease were included in this...
Myopia-protective against diabetic retinopathy
This meta-analysis evaluates the current evidence of the relationship between myopia and diabetic retinopathy (DR) risk. A systematic search was performed up to April 2015. Three models were used to assess the association between myopia and risk of DR: axial...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Conventional vs. accelerated cross-linking
The Dresden protocol of 3mW/cm2 irradiance for 30 minutes has been extensively studied and has shown advantageous clinical and topographical results. However, this protocol is time-consuming and therefore accelerated CXL using higher irradiance to shorten treatment duration has emerged. The...
