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3112 results found

Cataract surgery and circadian photoentrainment

The study authors sought to investigate the possible effects of circadian photoentrainment following cataract. This was a randomised clinical trial, where 76 eyes of 76 patients (with bilateral cataract) were randomised to blue-blocking or neutral intraocular lenses (IOLs). Outcome measures...

Conversion to strabismus and amblyopia

This study was undertaken to evaluate the incidence of true manifest strabismus, the visual acuity at school screening and whether risk of failing screening is different in those discharged at first visit or followed up. The author reviewed 248 children...

Radiotherapy for orbital apex cavernous haemangiomas

This is a review of six patients with cavernous venous malformations (haemangiomas) involving the orbital apex who were treated with fractionated stereotactic radiotherapy. Patients were diagnosed on MRI imaging with only one having had previous surgery to debulk the lesion....

SLT versus medication for OAG

This paper appraised existing randomised clinical trials (RCTs), which compared selective laser tabeculoplasty (SLT) with medical therapy for open-angle glaucoma (OAG), and performed a systematic review and meta-analysis. A total of 1229 patients in eight trials were included from PubMed,...

Likelihood of developing multiple sclerosis after optic neuritis diagnosis

Optic neuritis (ON) is a relatively common cause of acute optic neuropathy in young patients which often presents as the first sign of multiple sclerosis (MS). There is a lack of evidence around the factors that are associated with the...

Quantum imaging research could improve retinal scans

New EU-funded feasibility project is testing a quantum approach that could reveal finer detail in the eye than ever before. A European research consortium is exploring a new quantum imaging technique that could one day help clinicians see the earliest...

Effective treatment for rare sight-threatening infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

Has ‘reduce, reuse and recycle’ gone too far?

The past few decades of surgery since the ‘mad cow disease’ have been dominated by a push to switch to disposable instruments. The reason is to prevent cross-contamination and reduce the risk of surgical site infections – especially so with...

Bacterial keratitis through the window of the known unknowns

This review article provides an up-to-date summary of current challenges in research and management of bacterial keratitis. The authors highlight that there is no current agreement on the criteria that should define bacterial keratitis; the role of investigation is unclear,...

Establishing an intra-arterial chemotherapy service for children with retinoblastoma in Nigeria for the first time

This is the first in a series of three articles (see Part 2 here) about strengthening eye health services in Nigeria through collaboration with the LINKS and Networks run at the International Centre for Eye Health, London School of Hygiene...

The structure function relationship in glaucoma

Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...

Fight for Sight to maximise impact by funding solutions-focused research in priority eye conditions

Fight for Sight aims to stop sight loss by funding pioneering research. Rod McNeil takes a look at the Primer Fellowship Awards programme, which provides funding for up to £60,000 for individuals to undertake vision-related research for one year. Among...