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Retinoblastoma, CureAll and the role of global clinical, capacity strengthening and research networks
Retinoblastoma (Rb), a rare childhood eye cancer, presents a particularly compelling example of how global health partnerships can operate at the intersection of different medical disciplines, in this case: ophthalmology, oncology and public health. This article places the work of...Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...Cutting-edge practice in glaucoma care: what, how and why?
More effective treatments and drug delivery modalities, implantable minimally invasive glaucoma surgical (MIGS) devices, as well as accelerating clinical research programmes, will transform the surgical and clinical management of glaucoma in the near future. There is also an ever-greater emphasis...The past and the future for paediatric ophthalmology
The past 25 years have seen remarkable advances in clinical eye care for children in the UK. This has led to both improved outcomes and better patient and family experiences. There have been substantial changes to patient pathways, major advances...
Enucleation refusal for retinoblastoma
Retinoblastoma is the most common eye cancer in childhood, with enucleation rarely being the only lifesaving surgical option, especially where evidence of extraocular spread is apparent. This study sought to survey a global pool of eye care professionals with regards...
Ologen Collagen Matrix to treat ocular hypotony after filtration glaucoma surgery
The authors report a retrospective, observational case series of a Japanese cohort. 12 consecutive implantations of ologen in nine eyes of nine subjects (five men, four women; mean age ±SD, 72.1±12.7 years) who underwent subconjunctival implantation of the device to...
Non-arteritic anterior ischaemic optic neuropathy in the Asian population
This article provides an evaluation of changes in visual function associated with non-arteritic anterior ischaemic optic neuropathy (NAION) among Korean patients. Visual changes were identified as a reduction in visual acuity by three Snellen lines or a deterioration of visual...
Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients
For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...
Clinicopathologic factors and survival in patients with sebaceous carcinoma of eyelid
This is a population-based analysis performed to evaluate the prognostic factors and survival of patients with sebaceous carcinoma of the eyelid. Patients with eyelid sebaceous carcinoma from 1973-2013 were identified from the Surveillance, Epidemiology and End Results (SEER) database and...
Could internuclear ophthalmoplegia aid differential diagnosis in demyelinating conditions?
The authors present a retrospective review of individuals diagnosed with either neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). The aim of the study was to assess the prevalence of internuclear ophthalmoplegia (INO) in both groups over a 10-year...
Incidence of high IOP following corneal collagen cross-linking
This retrospective cohort study examined 405 patients (405 index eyes and 218 untreated fellow eyes) who underwent cross-linking over a 12-year follow-up duration at Duke Eye Center. Preoperative and postoperative intraocular pressure (IOP) measurements were collected at ~1 month, 3...
