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American Journal of Ophthalmology cover image.

Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

1 December 2014 | | EYE - Vitreo-Retinal
In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Trends in Opthalmology hosts Grand Ball in honour of Sir Harold Ridley 70th anniversary

5 February 2020
Sir Harold Ridley spent his working career at St Thomas' and Moorfields Hospital specialising in ophthalmology. During World War II, Ridley saw Royal Air Force casualties with eye injuries and observed that when splinters of acrylic plastic from aircraft cockpit...
Experimental Eye Research cover image.

Characteristics of limbal lymphatic vasculature on confocal microscopy

4 February 2021 | | EYE - Cornea, EYE - General
This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...
Experimental Eye Research cover image.

Review of pathogenesis of Acanthamoeba keratitis

4 February 2021 | | EYE - Cornea, EYE - General
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...
Eye journal cover image.

Ranibizumab safety in pregnancy

1 December 2018 | | EYE - Vitreo-Retinal
Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...

Existential Crises

1 June 2022 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Over the past few years and months, I have noticed increased numbers of my colleagues from all over the UK complaining about various problems with their jobs and life in general, and it seems that since the COVID-19 pandemic the...

The management of antiplatelets and anticoagulation in elective ophthalmic surgery

1 April 2016 | | EYE - Orbit, EYE - Oculoplastic
Clinical scenario: A 57-year-old gentleman who is scheduled to have Mohs micrographic surgery and reconstruction for a medial canthal basel cell carcinoma (BCC) has been started on aspirin and clopidogrel following a coronary stent three weeks ago. Does the antiplatelet...

The original smooth operator: Sir Robin Millar

4 December 2023 | | EYE - General
As an early 80s kid, if you lacked sufficient pocket money, building a music collection entailed recording your favourite songs off the radio with a cassette deck and hoping the presenter didn’t interrupt at any point, with a finger hovering...

Robotic assisted orbital surgery (RAOS) – a novel approach to orbital malignancy surgery

3 June 2024 | | EYE - Orbit, EYE - Oculoplastic, EYE - General
Robotic technology in ENT surgery has been used in certain areas of head and neck cancer care but, in this article, we hear of an exciting development from the team at Guy’s & St Thomas’. Advances in surgical robotic technology...

Keep calm and cut the carbon – improving sustainability in ophthalmology

7 December 2020 | | EYE - General
As I dump my tenth pair of gloves into a non-recyclable clinical waste bin; dispose of another handful of plastic minims; or print another wad of single-sided discharge paperwork after a cataract surgery, the inconvenient truth of how these seemingly...

Second sight: Ian McKinley

4 October 2023 | | EYE - General
I have always been captivated by a true-life story demonstrating the human spirit of triumph over adversity. For me, one of the most memorable sportsmen overcoming an injury has always been the mountaineer Joe Simpson and his tale of survival...

What's trending Aug/Sep 2025

4 August 2025 | | EYE - Orbit, EYE - Cornea, EYE - Oculoplastic
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Euros #Lionesses What a treat it is to be a football fan at the moment. An enthralling season in the Premier...