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A closer look at the new wave of glaucoma surgery – radical or old school?

Glaucoma is a challenging condition to treat because the exact pathophysiology remains unclear and the only readily modifiable factor is the intraocular pressure (IOP). Additionally, most glaucoma patients are completely asymptomatic, yet are often subjected to lifelong medical therapy. The...

The refractive index in the eye lens – implications for clinical practice and optical design

The eye may appear to be a comparatively simple organ and yet its optical system is complex and continues to be a source of investigation and research. The major optical elements are considered to be the cornea and the lens...

Well-presented scholarly research work will reduce chances of journal rebuttal

Submitting to an academic journal? Are you aware of the requirements and constraints of relevant copyright laws? Rod McNeil provides a guide for aspiring authors. Getting published in peer-reviewed academic and medical journals is not easy. But careful attention to...

Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Assessing the effectiveness of undergraduate ophthalmic assessments in the UK: A literature review

During 2008–2009, 300,000 patients presented to hospital emergency departments in the UK with eye conditions. This rose by nearly 200,000 over the next decade. As the population ages, the prevalence of eye disease increases [1,2]. However, the stake ophthalmology holds...

Developing a unified approach to low-vision care

RNIB’s Preeti Singla and Louise Gow introduce the Adult Low Vision Service Quality Framework. For individuals living with visual impairment, access to high-quality low vision services can be life changing. Yet, across the UK, these services remain fragmented, with significant...

Comparison of corneal deformation parameters in keratoconic and normal eyes

This study set out to compare biomechanical properties between normal and keratoconic eyes. It was a retrospective study evaluating 89 eyes (47 normal, 42 keratoconic) and a validation arm of 72 eyes (33 normal, 39 keratoconic) using a high speed...

High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema

The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...

Intravitreal dexamethasone implant for recurrent CMO secondary to IGS

In this prospective study the authors present the data obtained on the efficacy and safety of the dexamethasone implant (0.7 mg) in the treatment of recurrent cystoid macular oedema (PCME) due to Irvine–Gass syndrome in patients with uncomplicated pseudophakia (off-label...

Review of non-arteritic anterior ischaemic optic neuropathy

This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...

Bandage contact lens cultures after corneal collagen cross-linking

Corneal collagen cross-linking (CCL) is a treatment modality that has been shown to stop the progression of keratoconus. There have also been reports that CCL acts as an antimicrobiologic agent in treating resistant microbial keratitis. This study aimed to investigate...

Long-term outcomes of intravitreal ranibizumab for neovascular AMD

This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...