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A case report showing the natural history of papilloedema
1 June 2019
| Claire Howard
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EYE - Neuro-ophthalmology
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Optic cup, intracranial hypertension, papilloedema
The case report describes a 54-year-old woman who developed increased intracranial hypertension due to chronic dural venous sinus thrombosis in the absence of any significant comorbidity. In the years preceding diagnosis, the patient underwent routine diabetic retinopathy screening; however, gradual...
Retinal vessel diameter in pseudoexfoliation
5 February 2020
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
Pseudoexfolation (PEX) is characterised by deposition of fibrillary extracellular material on ocular and extraocular tissue. Studies have shown that deposition in vascular structures cause hypoxia and ischaemia. In the eye, a decrease in blood supply to the optic nerve can...
A case of ipsilateral fourth nerve paresis and Horner’s syndrome
1 April 2020
| Claire Howard
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EYE - Neuro-ophthalmology
The author presents a single case report of an exceptional association between fourth nerve palsy and ipsilateral Horner’s Syndrome. The case is presented alongside magnetic resonance images (MRI) which reveal a mass in the right cavernous sinus. The 54-year-old woman...
Perceptual learning treatment for amblyopia
The authors previously conducted a feasibility study examining the potential benefit of a self-administered at-home use of a tablet-based perceptual learning (PL) game. Visual stimuli were presented in various orientations and spatial frequency in a game-play format. This study evaluates...Using MRI to assess normal variation in optic chiasm anatomy
4 August 2021
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present an MRI study including 61 MRI scans using a 1.5 T with slice thickness of 1 or 5mm and the sequence showing the highest resolution of the chiasm. A predetermined set of measurements were taken in a...
FA findings in treatment-naive premature infants
This retrospective study examined fluorescein angiography (FA) images of 162 eyes of 81 treatment-naive infants with retinal vascular immaturity and persistent avascular retina (PAR) despite exceeding postmenstrual age of 60 weeks. Disc diameter (DD), optic disc-to-fovea distance (FD), the length...Natural history of idiopathic intracranial hypertension depending on incidental or symptomatic presentation
3 February 2023
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a large retrospective review cohort of consecutive patients diagnosed or presumed idiopathic intracranial hypertension (IIH) over a three-year period at a single tertiary centre. Patients on medication with a known aetiology for IIH were excluded. The cohort...
Progression of macular atrophy in Stargardt disease
3 April 2024
| Ian Reekie
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EYE - Vitreo-Retinal
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
A novel parameter for angle closure
4 February 2025
| Jonathan Chan
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EYE - Glaucoma
This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...
The ‘theatre of the mind’: Charles Bonnet Syndrome and Esme’s Umbrella
The founder of Esme’s Umbrella shares her experience with the poorly understood condition Charles Bonnet Syndrome and the creation of the campaign. Many years ago, when I was a young actress, I was in an American play called ‘Butterflies are...Mastering clinical skills in ophthalmology
3 October 2022
| Sammie Mak, Zaria Ali
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EYE - General
To young junior doctors, and some senior doctors who may not have had much exposure to ophthalmology, the specialty can seem very foreign. Not only are the conditions and examination findings specific to the eyes, but the skill set required...