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Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

The past and the future for paediatric ophthalmology

The past 25 years have seen remarkable advances in clinical eye care for children in the UK. This has led to both improved outcomes and better patient and family experiences. There have been substantial changes to patient pathways, major advances...

Blurred vision post liver transplant: to blame the house cat or not?

This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...

Ocular ischaemic syndrome in a rat model

Ocular Ischaemic syndrome is a devastating eye disease caused by severe carotid stenosis. This study’s purpose was to develop a reliable rat model for this syndrome by subjecting rats to common carotid artery occlusion and sham surgery. Rats were assigned...

Early intraocular complications of aneurysmal subarachnoid haemorrhage

The aim of this study was to estimate the incidence of a whole spectrum of early intraocular complications in patients suffering from aneurysmal subarachnoid haemorrhage (SAH) and to identify factors that are potentially associated with these fundus findings. In total...

Intra-arterial carboplatin therapy not associated with hearing loss

The aim of this study was to determine if administration of intra-arterial carboplatin (IAC) affected the hearing of children being treated for retinoblastoma. This was a prospective study in which 22 of 40 consented children completed therapy. Hearing was tested...

Effect of intra-arterial chemotherapy drug regimens on globe salvage outcomes of retinoblastoma patients

This is a retrospective study from Shandong University, China, between May 2016 to November 2019, to compare the effect of 3-drug regimen (melphalan (MP) , topotecan (TP) and Carboplatin (CP)) of 95 patients (97 eyes) with two-drug regimen (MP and...

Nonarteritic anterior ischaemic optic neuropathy

This review article describes nonarteritic anterior ischaemic optic neuropathy (NAION). This condition is one of the common causes of visual loss in adults. The article uses a good range of references and is divided under the headings of; demographics, clinical...

Choroidal and macular thickness in nonarteritic anterior ischaemic optic neuropathy

This study evaluates the choroidal and macular thickness in patients with chronic nonarteritic anterior ischaemic optic neuropathy (NA-AION). Two groups of subjects were compared, group one included 20 eyes with chronic NA-AION and group two, 31 healthy control eyes. The...

My Top Five: Key insights from recent research into uveitis in adults

Uveitis, characterised by inflammation of the uvea – the eye’s middle layer comprising the iris, ciliary body, and choroid – remains a leading cause of visual impairment worldwide [1]. It primarily affects adults aged 20–50 years. Untreated uveitis may cause...

Acute management of retrobulbar haemorrhage

The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Ocular complications in retinal vasculitis

In this retrospective study the authors aimed to characterise the incidence rates of visual loss and ocular complications associated with retinal vasculitis (RV – annual incidence of 1-2/ 100000/ per annum). A secondary objective was to compare the visual outcomes...