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A revolution in modern genetic testing for the clinical management of ocular disease

1 August 2016 | | EYE - Cataract, EYE - Pathology, EYE - Vitreo-Retinal
Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...

My Top Five: Debunking common myths in ophthalmology and vision care

29 August 2024 | | EYE - General
In the field of eye health, numerous misconceptions persist. Let’s examine five prevalent myths and uncover the truth behind them. Myth 1: Wearing glasses weakens your eyesight Origin: This myth likely originated from the observation that people often need stronger...

Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress

2 August 2024 | | EYE - General
Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...

The challenge of chorioretinal folds in virtual eye clinics

3 June 2024 | | EYE - Vitreo-Retinal, EYE - Orbit
Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

Principles of contact lens fitting in keratoconus

1 December 2015 | | EYE - Cataract, EYE - Refractive
Keratoconus is an ectatic condition of the cornea characterised by progressive conical distortion with irregular astigmatism, myopia and apical protrusion. Most cases progress slowly resulting in varying degrees of myopic astigmatism. Management of keratoconus includes spectacles, soft contact lenses, a...

Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

1 October 2018 | | EYE - General
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | EYE - Vitreo-Retinal, EYE - General
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Unravelling ocular motility

1 April 2016 | | EYE - Neuro-ophthalmology
Ocular motility can often be a slightly abstract concept during the earlier years of ophthalmology training. A large variance on what embodies normality; mythical concepts like fusion and binocular vision, examination techniques that can be fiddly, and complex neuroanatomy all...

Cancer associated retinopathy

7 December 2020 | | EYE - Vitreo-Retinal, EYE - General
Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...

Optic nerve swelling – your survival guide (part 1)

1 August 2017 | | EYE - Neuro-ophthalmology
Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | EYE - Glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...