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1976 results found

MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Ocular adnexal marginal zone b-cell lymphoma

This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...

Online retinoblastoma surveillance tool

Given the vision and life-threatening course of retinoblastoma (RB), it has become a significant heritable childhood cancer to screen for. To recommend surveillance, risk must be estimated and genetic testing plays a vital role. However, genetic tests vary based on...

Second primary tumours after sebaceous carcinoma

This is a study investigating the risk of developing a second primary malignancy in patients previously diagnosed with eyelid sebaceous cell carcinoma. The records of 559 patients who were diagnosed with sebaceous cell carcinoma between 2000 and 2016 were reviewed,...

Using a tumour registry to investigate optic nerve gliomas

This study is a retrospective comparative analysis. Patients with optic nerve glioma and pilocytic astrocytoma were identified through the Surveillance, Epidemiology and End Results (SEER) cancer registry covering a 42-year period using standardised codes. The following data was extracted: basic...

Long-term incidence and survival trends in retinoblastoma in the USA

The authors present a retrospective observational study of 5730 patients diagnosed with retinoblastoma between 1996 and 2018. Data on demographics, age at diagnosis, treatment and survival were extracted from national registries with coverage of 99% of the population of the...

RCOphth (The Royal College of Ophthalmologists) Cornea Curriculum Course

Surgical skills, two-day-course on Corneal transplantation (penetrating keratoplasty, DALK, DSEK, PDEK and DMEK), and Common Corneal procedures (Suturing, gluing, Amniotic membrane suturing corneal laceration).Wet Lab training on common corneal procedures, PKP and DALK. Suitable for mid-career trainees and early career...

Med Sales Academy: Introduction to Medical Device Sales

We are serious about providing you with more than a course, we offer you a framework for success and a support network as you embark on a career in medical sales. Our Online Introduction to Medical Sales Course is aimed...

Mad world

The early 1980s were a glorious time to be a teenager. Along with BMX bikes, Airwolf and Quattro, we had a plethora of new music genres to be enthralled by. The band Frankie Goes to Hollywood with their dance /...

More Than Just a Call: RNIB’s Talk and Support Groups combatting loneliness

Every Thursday at 11am, something quietly powerful happens across Scotland. Phones ring, voices chime in, and a group of blind and partially sighted people connect for an hour that’s full of laughter and real talk. It’s an RNIB Talk and...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...