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Congenital cataract

Congenital cataract is the clouding or opacification of the lens that occurs at birth or weeks after (infantile cataract). They can be unilateral or bilateral and vary in form, size and location, and consequently the visual impact, management course and...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Update on emerging therapies for age-related macular degeneration

The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...

Part 1: The Arclight Project – Frugal tech for sight

Click here for Part 2 on this topic, and here for Part 3 The Arclight Project is a mix of frugal design, manufacturing, distribution, teaching, research, and advocacy, all wrapped up in a social enterprise based at the University of...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Diabetic Retinopathy Network laser training programme

The VISION 2020 Diabetic Retinopathy Network (DR-NET) was established in 2014 to tackle the increasing burden of diabetes and diabetic retinopathy (DR) in developing countries [1]. By forming a network of long-term LINK capacity-building partnerships, learning and best practice can...

What’s new in wet AMD papers?

Paper presentations on neovascular (‘wet’) age-related macular degeneration (AMD) from the 16th European Society of Retina Specialists Congress, Copenhagen, September 2016, outline recent research directions evaluating the impact of vision loss on key health domains, patient preferences in the process...

Working smarter not harder: How to transform eyecare delivery in the United Kingdom (part 1)

Are we doing enough to meet the current demands on ophthalmic services? In part one of a two-part series (see Part 2 here), Rosalind Harrison takes a look at how efficiency has been improved in eyecare services in the US....

Dark circles and facial rejuvenation

A 45-year-old socialite lady comes for cosmetic consultation and wants a remedy for dark circles and facial ageing. How do you manage this patient? Issues of dark circles and facial ageing should be addressed separately. Facial ageing should be considered...

Simulation in ophthalmology: a pedagogic viewpoint

The advent of simulation technology has enhanced modern medical training. The first utilisation of simulation was in 1929 where Edward Link used this concept to develop a mechanical flight simulator [1]. Industries such as aviation, nuclear power and the military...

Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

Bionic eyes: deciphering the neural circuitry of vision restoration

As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...