Journal Reviews archive for 2019
Acetazolamide and CMO
The authors set out to analyse the effect of acetazolamide therapy on inflammatory cystoid macular oedema (CMO) as defined by change in central macular subfield thickness (CST), as well as its effect on visual acuity. A retrospective chart review was...
Atrophy and anti-VEGF
The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...
Control of bleeding with diabetic vitrectomy under air
The authors describe a modified diabetic vitrectomy using continuous air infusion in diabetic eyes with severe fibrovascular proliferation. In their case series of 25 eyes (20 patients), intravitreal bevacizumab (1.25mg) was used one week prior to surgery. Fifteen eyes had...
Endophthalmitis after intravitreal anti-VEGF injection
The authors report the results of a retrospective multicentre study conducted at 17 retina referral centres to investigate the microbial spectrum of endophthalmitis after anti-VEGF injections. A total of 83 cases of culture-positive endophthalmitis (58.4%) were included. The most frequent...
IOP in children with uveitis
This is a retrospective study of paediatric uveitis (<16-years-old) between July 2002 to June 2016 of a total of 320 children from a single centre: 17.2 % (55/320 patients) developed raised IOP requiring therapy; 11.5% of eyes required glaucoma surgery...
Lacquer cracks
The purpose of this Japanese study was to analyse the morphologic features and natural progression patterns of lacquer cracks (LC). The presence of linear hyperfluorescence on the fundus fluorescein angiography (FFA) was used as the standard for diagnosing the presence...
Subthreshold micropulse laser in BRVO
The purpose of this retrospective, consecutive, single-centre, non-randomised, and case-control study was to verify the therapeutic effects and safety of oedema (from branch retinal vein occlusion (BRVO)) recurrence suppression effect using 577-nm subthreshold micropulse laser photocoagulation (SMLP) in combination with...
Effect of cataract surgery on inflammation control and vision in uveitis patients
This retrospective longitudinal study from Moorfields, London, UK compared uveitis recurrence rates and vision loss in 309 eyes of uveitis patients post cataract surgery to 300 control uveitis patients. Cataract is a common complication associated with uveitis and leads to...
Combined PRK and CXL in keratoconus
This study aimed to investigate the results after photorefractive keratectomy (PRK) followed immediately by standard 30-minute corneal cross-linking (CXL) for keratoconus. This retrospective study included 26 eyes of 16 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual...
Ripasudil after Descemet stripping in Fuch’s endothelial dystrophy
This study prospectively evaluated the use of ripasudil, a rho kinase inhibitor, in patients undergoing Descemet’s stripping only (DSO) without an endothelial graft for Fuch’s endothelial dystrophy (FED). Patients with dense central guttae limited to the central 5mm of the...
Can intravitreal anti-VEGF injections affect corneal nerves?
This was a retrospective case-control study looking at the effect of anti-VEGF injections on corneal nerves (CN). Fifty-seven patients with a history of at least three anti-VEGF injections in one or both eyes and available confocal microscopic imaging were included...
The incidence of retinal vein occlusion in patients with pseudoexfoliation glaucoma
In this retrospective study the authors aimed to evaluate PXF as an independent risk factor for the occurrence of retinal vein occlusion (RVO). Three hundred PXF glaucoma patients (PXF group), 300 non-PXF glaucoma patients, and 599 non glaucoma non-PXF (nGnP...
