Journal Reviews archive for April 2015
Effect of selenium and vitamin E supplements on the development and progression of cataracts
The Selenium and Vitamin E Cancer Prevention Trial (SELECT) investigated the influence of dietary supplements on the development of prostate cancer in a group of 35,533 middle aged and older, apparently healthy men. The SELECT Eye Endpoint (SEE) study is...
Results after 1.4mm biaxial cataract surgery and implantation of a new aspheric intraocular lens
The aim of this study was to analyse the clinical outcome and higher-order aberrations (HOAs) after 1.4mm biaxial micro incision cataract surgery (B-MICS) and implantation of a new aspheric intraocular lens (IOL). A total of 157 eyes of 106 patients...
Is there an association between dry eye disease and depression and anxiety?
Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...
Effect of topical diclofenac on postoperative PRK pain: RCT
A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...
Risk factors for NTG in a young Korean population
Previously known ocular and systemic risk factors for normal tension glaucoma (NTG) include myopia, peripapillary atrophy, disc haemorrhage, migraine, obstructive sleep apnoea, thyroid disease and cerebral infarction. However, most NTG risk factor studies have examined patients aged 40 years and...
Conjunctival inflammation in glaucoma patients
Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...
Implantation of intraocular pressure sensor in glaucoma patients
The authors report safety and accuracy of an intraocular intraocular pressure (IOP) sensor placed in the ciliary sulcus during planned cataract surgery. Six patients underwent implantation of the device; a silicone rubber ring-shaped device encapsulating pressure sensitive capacitors and a...
Brn3b neuroprotective effect in rat glaucoma model
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...
SLT vs. topical treatment with prostaglandin analogues in the management of PACG
Selective laser trabeculoplasty (SLT) has been shown to be useful in the management of primary open angle glaucoma (POAG), but its use in primary angle closure (PAC) / primary angle closure glaucoma (PACG) has yet to be validated. Narayanaswamy et...
Visual recovery following Ex-Press vs. trab
The authors describe a prospective randomised study of 64 POAG subjects with controlled IOPs comparing visual acuity data in patients randomised to either Ex-Press model P50 or trabeculectomy. Visual acuities were recorded at baseline, day one, weeks one and two...
Eye drop prescription and usage in glaucoma patients
The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma...
Full thickness macular hole after YAG PI
The authors report a case of macular hole post YAG peripheral iridotomy (PI) of a patient with pre-existing vitreomacular adhesion. Although a relatively safe procedure, some anterior segment complications are well documented such as corneal endothelium damage, rise in IOP,...
