The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma medications including a prostaglandin bilaterally. Demographic data was collected, as well as number of bottles prescribed monthly and a five item questionnaire was used to evaluate eye drop administration. Their findings show that patients’ routine medication usage was significantly associated with the number of bottles prescribed monthly. The authors suggested that this was reflective for patients who tended to miss the eye when instilling the eye drops probably because of incorrect technique. Their results also showed that men or patients with mild glaucoma were less likely to be aware of local side-effects than women or patients with severe glaucoma. Limitations of the study include small sample size, practice pattern in Japan and the need for further prospective studies with a larger number needed.