Journal Reviews
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
The global burden of age-related macular degeneration
Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...
IOL tilt with air tamponade vs. salt solution
In this study the authors made a comparison of significant postoperative tilt of IOL with air tamponade as opposed to balanced salt solution, in the procedure of combined phaco with IOL and vitrectomy. Thirty-four patients were included into the analysis....
RPE atrophy onset in treated nAMD
In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...
Viral uveitis
This review covers viral causes of anterior uveitis. A viral aetiology should be suspected when anterior uveitis is accompanied by ocular hypertension, diffuse stellate keratic precipitates or the presence of iris atrophy. Most common viruses associated are herpes simplex, varicella-zoster...
Aberration measurements with manual or FLA cataract surgery
This study group compared the higher order aberrations (HOAs) between femtosecond laser-assisted cataract surgery (FLACS) and manual cataract surgery. Consecutive patients undergoing FLACS or manual cataract surgery with implantation of an intraocular lens from January 2017 to February 2018 were...
Management of restrictive diplopia after ptergium surgery
This single centre retrospective case series included 15 patients with restrictive diplopia after ptergium excision. The mean time from surgery to diplopia was six months and all patients had a moderate limitation of abduction in the operated eye causing an...
Association of dry eye symptoms in patients with dyslipidaemia and statin use
This retrospective analysis of the Blue Mountains Eye Study III cohort (Caucasian Australians residing west of Sydney n=1680; mean age >74 years, range 60-97) analysed the association between dyslipidaemia, use of oral statins and symptoms of dry disease (DED) among...
Can closing the eyelid during riboflavin induction phase of crosslinking increase corneal thickness?
Corneal crosslinking (CXL) with riboflavin and UVA irradiation is the standard treatment for preventing progression of keratoconus. Thinning of the cornea during the riboflavin loading phase was reported in previous studies which used riboflavin with dextran. A minimum stromal thickness...
Comparing femtosecond laser assisted-DMEK to manual DMEK
Femtosecond laser is as a novel tool for performing precise descemetorhexis in descemet membrane endothelial keratoplasty (DMEK) surgery. In DMEK surgery, the recipient’s Descemet membrane is peeled to allow adherence of the donor DMEK tissue to the recipient’s stroma. Complete...
Ocular manifestation of Marfan Syndrome
This repeated cross-sectional study collected data in 2003-2004 and 2014-2015 to investigate changes in ocular features in Marfan syndrome (MFS) fulfilling the Ghent-2 criteria. Ghent-2 is a set of criteria by which MFS are identified and includes aortic root aneurysm...
How are pigment dispersion syndrome and pigmentary glaucoma inherited?
This single centre prospective, cross-sectional study assessed the relatives of patients with pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) to determine the heritability of these conditions over an 11 month period. One hundred and one unrelated patients with PDS...
