This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.  Read our Cookies Policy.
Close
Eye News
  • Features
    • Close
    • Features
    • Allied Professions
    • Humanitarian
    • Interviews
    • AI & Oculomics
    • Ophthalmology
    • Optometry
    • Podcast videos
    • Supplements
  • Education
    • Close
    • Education
    • Learning Curve
    • Quiz
    • Top Tips
    • Trainees
    • Medico-Legal
    • The Truth Behind The Headlines
    • Case Reports
    • Pete's Bogus Journey
  • Reviews
    • Close
    • Reviews
    • Book Reviews
    • Journal Reviews
    • What's trending?
    • Tech Reviews
    • My Top Five
    • The Culture Section
  • Events
  • News
  • Product Guide
  • Industry News
  • Contact us
    • Close
    • Contact us
    • Write for Eye News
  • Home
  • Reviews
  • Journal Reviews
  • App detection of leukocoria

App detection of leukocoria
Reviewed by Fiona Rowe

5 August 2020 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus
Share This

This paper outlines ARCELE – Computer Assisted Detection of Leukocoria. This is an iPhone app developed to increase early detection of retinoblastoma by detecting leukocoria. The aim of this study was to determine the use of CRADLE as a screening tool in clinical practice. This was a prospective study of 244 eyes of 122 children aged one to six years; 52% were males. Of these children, nine had cataract, one stage five retinopathy of prematurity (ROP) and three had retinoblastoma. Leukocoria was evaluated in all by penlight or ophthalmoscope. The app detected two eyes of the same patient with bilateral retinoblastoma. None of the cataract eyes were detected by the app. Therefore, there were 11 false negatives and 0 false positives. Sensitivity of the app was 15.38% and 100% specificity. Negative likelihood ratio was 0.85. The authors conclude the app may be a valuable support to parents. However, it cannot be considered as an alternative to the use of an ophthalmoscope. 

Evaluation of a free public smartphone application to detect leukocoria in high-risk children aged 1 to 6 years.
Vagge A, Wangtiraumnuay N, Pellegrini M, et al.
JOURNAL OF PEDIATRIC OPHTHALMOLOGY AND STRABISMUS
2019;56:229-32.
Share This
Fiona Rowe (Prof)
CONTRIBUTOR
Fiona Rowe (Prof)

Institute of Population Health, University of Liverpool, UK.

View Full Profile
Specialty
  • EYE - Cataract
  • EYE - Cornea
  • EYE - General
  • EYE - Glaucoma
  • EYE - Neuro-ophthalmology
  • EYE - Oculoplastic
  • EYE - Oncology
  • EYE - Orbit
  • EYE - Paediatrics
  • EYE - Pathology
  • EYE - Refractive
  • EYE - Strabismus
  • EYE - Vitreo-Retinal
Archive
  • 2025
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013

Top Of Page

9 Gayfield Square, 
Edinburgh EH1 3NT, UK.

Call: +44 (0)131 557 4184
www.pinpoint-scotland.com

WEBSITE DETAILS
  • Cookie Policy
  • Data Protection Notice
  • Privacy Policy
  • Terms and Conditions
ABOUT US
  • Who we are
  • Register
  • Contact us
  • Contributors
  • Company Awards
DIGITAL ISSUES/GUIDELINES
  • Digital issues - Library
  • Supplements - Library
  • Guidelines
Accreditations
IPSO_FLAG_TEAL 2025.png cpdcertified.png

Pinpoint Scotland Ltd (Registered in Scotland No. SC068684) | © 2025 - Website by Gecko Agency