Journal Reviews
A novel presentation of optic disc oedema with syphilis
Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....
Mechanism of colour vision involvement in multiple sclerosis
There is evidence to show that the optic nerve and retina are affected in multiple sclerosis (MS) even without any clinical evidence or history of optic neuritis (ON). MS without optic neuritis causes colour-vision deficit, however, the evidence for selective...
Using small amplitude saccades to assess saccadic velocity
Saccades are a key component in the assessment and diagnosis of neuro-ophthalmological disorders. Clinicians are typically taught to use large amplitude saccades (LAS) of at least 20 degrees to assess saccadic velocity. It has been suggested, however, that small amplitude...
Saccadic eye movements in young-onset Parkinson’s disease
The objective of this study was to understand control of saccadic eye movements in patients with young onset Parkinson’s disease (YOPD) where onset of disease symptoms appears early in life (<40 years of age). Functional magnetic resonance imaging (fMRI) was...
Ocular adnexal marginal zone b-cell lymphoma
This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...
Quality of life concerns after uveal melanoma diagnosis
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
Support for patients with nystagmus
This is a qualitative study in patients with nystagmus identified through regional clinics, charity events and the Royal National Institute of Blind People (RNIB). Two hundred and fifty-one participants were identified, with 184 respondents included in the study. Fifty-six percent...
Mediation of vertical vergence
The authors hypothesised that if vertical vergence were mediated by vertical rectus muscles, then the eye that moves during a vertical fusion task would produce larger vertical vergence when abducted versus adducted. Similarly, if mediated by the oblique muscles then...
Lang Stereopad comparisons
The aim of this study was to compare the effectiveness of the Lang Stereopad in detecting and measuring stereopsis in a population with normal visual parameters. The Lang Stereopad was compared directly to the Frisby, TNO and Lang II stereotests...
Silicone oil migration presenting as an eyelid cyst
The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...
Medical treatment of orbital lymphatic malformations
This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...
