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This prospective clinical study compared retinal and peripapillary blood flow parameters in migraine patients during an attack with healthy controls using optical coherence tomography angiography (OCTA). OCTAs were performed on 52 eyes from 26 migraine sufferers and 48 eyes from 24 healthy controls, with RTVue XR Avanti using AngioVue software. OCTA imaging was performed during a migraine attack before any treatment was administered. Vascular density measurements in the superficial plexus were similar between migraine sufferers and controls (p>0.05). Vascular densities in the deep capillary plexus were similar between groups (p>0.05), except in the deep superior area (p=.05). Flow areas in the nerve head, vitreous, peripapillary capillary and choroid segments were similar between groups (p>0.05). Macular thickness parameters were also similar between groups (p>0.05). The results suggest that an acute migraine attack does not affect retinal or peripapillary blood flow.

Are retinal and peripapillary blood flows affected during migraine attack?
Guler O, Guler M, Buket Tugan Yildiz C, Hakkoymaz H.
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Claire Howard

Salford Royal NHS Foundation Trust, Salford, UK.

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