Influence of FLEx and SMILE on corneal nerve density and ocular surface
This was a prospective study designed to compare the influence of femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE) on the corneal nerve density and ocular surface for myopic correction. Thirty patients underwent bilateral lenticule extraction. One eye...
γδ T cell depletion does not affect fungal keratitis
1 August 2015
| Graham Wallace
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EYE - Cornea, EYE - General
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CFW, Cytokines, FK, Fungal keratitis, IL-17, Neutrophils, calcofluor WHITE, fungal keratitis, γδ T cells
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...
The impact of conjunctivochalasis on dry eye symptoms and signs
The study aimed to draw a relationship between conjunctivochalasis and dry eye symptoms via a dry eye questionnaire (DEQ5), as well as signs such as tear osmolarity, tear break up time, corneal staining, Schirmer score, meibomian gland dropout, eye lid...
Allografts in limbal stem cell deficiency
1 August 2015
| Saruban Pasu
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EYE - Cornea, EYE - General
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Cadaveric keratolimbal allograft, limbal stem cell deficiency, limbal stem cell transplantation, live related allograft
This prospective comparative study compared outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency secondary to ocular burns. Twenty patients were randomly allocated into each group. The Lr-CLAL group had a significant...
Topical atorvastatin for dry eye and blepharitis
Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...
Cytotoxic effect of voriconazole on human corneal epithelial cells
Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...
Sustained elevation of extracellular ATP in chronic glaucoma
1 August 2015
| Wai Siene Ng
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EYE - Glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
Postural control in glaucoma patients with virtual reality
1 August 2015
| Brian Ang
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EYE - Glaucoma
The authors report on a cross-sectional study evaluating postural control and history of falls in glaucoma patients. History of falls was obtained using the Falls Screening and Referral Algorithm. Postural stability was assessed using a force platform under four conditions:...
A case series of acquired esotropia in cerebellar disease
1 August 2015
| Claire Howard
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EYE - Neuro-ophthalmology
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Cerebellar degeneration, diplopia, esotropia, lateral rectus paresis
Acquired esotropia in cerebellar disease is well described but under-recognised. The pathogenesis of cerebellar esotropia is controversial. It is suggested it may be a result of disruption to central vestibular pathways. This article reports a case series of seven adults...
A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair
1 August 2015
| Claire Howard
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EYE - Neuro-ophthalmology
This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...
Neuro-ophthalmological symptoms in patients with cerebral venous sinus thrombosis
1 August 2015
| Claire Howard
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EYE - Neuro-ophthalmology
The authors of this article have evaluated the neuro-ophthalmological symptoms of 49 patients with cerebral venous sinus thrombosis. They have evaluated the onset of the disease as well as the symptoms reported. The authors present extensive clinical information for individual...
A case series of acute visual loss following excessive alcohol and / or drug use
1 August 2015
| Claire Howard
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EYE - Neuro-ophthalmology
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Ophthalmoplegia, retinal artery occlusion, saturday night retinopathy
This study presents three cases of so called Saturday night retinopathy, an acute visual loss following intravenous drug abuse and stupor, leading to continuous pressure on the orbit while asleep. All three cases presented with acute vision loss and had...
