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  • A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair

A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair
Reviewed by Claire Howard

1 August 2015 | Claire Howard | EYE - Neuro-ophthalmology

This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a gastric tube), emotional lability and ophthalmoplegia. The authors have provided a video of the patient to illustrate how profound these deficits were. The patient underwent extensive contrasted fat suppressed cranial and orbital MRI, MRI tractography and functional MRI. Given the extensive degree of neurological impairment, the authors expected this advanced neuroimaging to be abnormal, however, it revealed no clear radiographic involvement, except for a tiny hypoechoic midbrain dot which is not considered sufficient to account for the patient’s deficits. This case attests to the unknown and unusual nature of this rare and devastating syndrome. 

Functional magnetic resonance imaging (MRI) and MRI tractography in progressive supranuclear palsy-like syndrome.
Vaphiades MS, Visscher K, Rucker JC, et al.
NEURO-OPHTHALMOLOGY
2015;39(2):64-8.
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CONTRIBUTOR
Claire Howard

Salford Royal NHS Foundation Trust, Salford, UK.

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