Non-contact-lens-associated acanthamoeba keratitis
1 October 2015
| Jaya Myneni
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EYE - Cornea, EYE - General
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Acanthamoeba keratitis, microbial keratitis, microscopy, non-contact-lens, time of presentation
This retrospective study was done to study the clinical presentation and microbiological results of non-contact-lens-related acanthamoeba keratitis (AK). One hundred and ninety-four patients with microbiological / histopathological diagnosis of AK over four years were included. All patients had corneal scrapings...
Autophagy in lens mitochondria loss
1 April 2014
| Graham Wallace
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EYE - Cataract, EYE - Refractive
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ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...