Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
1 April 2018
| Graham Wallace
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EYE - Glaucoma
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
A case report of alternating anisocoria with associated nasal congestion
1 April 2018
| Claire Howard
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EYE - Neuro-ophthalmology
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Anisocoria, autonomic, nasal cycle, pupil
The authors have described a group of healthy individuals who show alternating anisocoria, in a previous paper. In these cases, the pupil asymmetry alternates between eyes every few hours, with no observed instances when both pupils are equal in size....
Could medical cannabis be used to successfully treat blepharospam?
1 April 2018
| Claire Howard
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EYE - Neuro-ophthalmology
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Blepharospasm, cannabis, marijuana, muscle spasm
This study observed the effect of medical cannabis in benign essential blepharospasm (BEB), in addition to standard botulinum toxin treatment. The study comprised of a retrospective chart review on eligible patients and included information on patient demographics, responses, cannabis history...
Development of testing protocols for high and low contrast visual acuity
1 April 2018
| Claire Howard
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EYE - Neuro-ophthalmology
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Amyotrophic lateral sclerosis, LCD tablet, high-contrast visual acuity, low-contrast visual acuity, pinhole
Dysfunction of the afferent visual system, characterised by impairments in high-contrast visual acuity (HCVA) and low-contrast visual acuity (LCVA) have been demonstrated in some neurological conditions such as multiple sclerosis and Parkinson’s disease. HCVA and LCVA are also potential quantitative...
Hemianopia or visuospatial neglect: differences in information processing
1 April 2018
| Claire Howard
|
EYE - Neuro-ophthalmology
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Eye movements, hemianopia, neglect, semantic priming
It is widely reported that visuospatial neglect and hemianopia may be superimposed, and disentangling the two conditions can be pose difficulties for clinicians. The authors of this paper explored the differences in implicit information processing which is effective in patients...
Association between colour vision impairment and amyotrophic lateral sclerosis (ALS)
1 April 2018
| Claire Howard
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EYE - Neuro-ophthalmology
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Amyotrophic lateral sclerosis, colour vision, desaturated L’Anthony D-15, retinal disease
The purpose of this study is to test the hypothesis that colour vision impairment is associated with amyotrophic lateral sclerosis (ALS). Abnormalities of the inner and intermediate retinal structures in patients with ALS have been described using optical coherence tomography...
Early diagnosis of pituitary apoplexy using combined MRI findings
1 April 2018
| Claire Howard
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EYE - Neuro-ophthalmology
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Pituitary apoplexy, pituitary ring sign, sphenoid sinus mucosal thickening
The author presents a literature review searching the terms ‘pituitary ring sign’ and ‘sphenoid sinus mucosal thickening’ in the context of pituitary apoplexy from 1990 until the present day. These two findings are both magnetic resonance imaging (MRI) signs of...
Treatment for post stroke visual impairment – clinical practice versus literature evidence
1 April 2018
| Claire Howard
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EYE - Neuro-ophthalmology
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Management, stroke, treatment, vision, visual impairment
The aim of this paper is to compare the treatments reported in a large scale stroke study (Vision in stroke (VIS) Study) against the treatments identified in a full systematic literature review. The purpose was to identify which treatment /...
Marcus Gunn jaw winking without ptosis
This is a review of 72 cases of Marcus-Gunn jaw winking syndrome. The authors reviewed all their congenital ptoses seen over a 16 year period and found 72 Marcus-Gunn cases of out of a total of 848 patients. Within the...
Outcomes of Hughes flap in lower eyelid reconstruction
One hundred and 22 consecutive patients who underwent tarsoconjunctival advancement flap surgery for lower eyelid defects were part of this study. Ninety percent of them had lesion excision using Mohs micrographic surgery. Eighty percent of these were for basal cell...
Systemic screening in adnexal lymphoma
This is a retrospective review of 119 patients diagnosed with ocular adnexal lymphoma, 85 of whom had primary adnexal disease and 34 had previously been diagnosed with lymphoma outside the ocular adnexa. Sixty-eight of the primary and 24 of the...
Visual field changes in thyroid eye disease (TED)
This study is a retrospective non- comparative review of visual field (VF) tests in patients with compressive optic neuropathy from thyroid eye disease (TED-CON). Ninety-six visual fields in 68 patients were included in the study and a two-step analysis of...
