Lamellar patch grafts utilising cornea remnants from DMEK/PKP
The authors retrospectively reviewed 23 lamellar patch grafts performed over a six-year period for tectonic indications in corneal thinning and perforations. The anterior stroma of corneal endothelium peeled for descemet membrane endothelial keratoplasty (DMEK) were used to prepare circular lamellar...
Hidden spread of sebaceous cell carcinoma
This was a review of 29 patients who had undergone orbital exenteration for sebaceous cell carcinoma. Prompted by the increasing use of topical treatments for intraepithelial disease, the authors were keen to discover the frequency of spread of tumour cells...
Transconjunctival eyelid weight insertion
This is a description of a new surgical technique to insert upper lid weights via a posterior, transconjunctival route. Following local anaesthetic, the upper lid was everted over a Desmarres retractor with a silk traction suture. A 5mm high central...
COVID-related mucormycosis
The authors report a retrospective case-control study of 73 patients with COVID-19 associated mucormycosis (CAM) between 1st March and 30th May 2021. They compared various factors between the two groups – patients who survived CAM (47 [64%]) and those that...
The incidence of sympathetic ophthalmia
In this meta-analysis, the authors looked at 24 retrospective studies to determine the incidence of sympathetic ophthalmia following open globe injury amongst adult and paediatric populations. The year of publication of studies included ranged from 1972-2019, and with broad search...
Transient visual loss caused by crowded optic discs
5 April 2022
| Claire Howard
|
EYE - Neuro-ophthalmology
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Young, amaurosis, crowded, female, optic disc, visual loss
The author presents four cases of transient visual loss (TVL) in young females (age range at presentation 14-22 years) with crowded optic discs. Patient demographics, investigations, medical and social histories are provided for all patients. A review of evidence for...
Assessment of slow and fast vergence in stroke survivors
5 April 2022
| Lauren R Hepworth
|
EYE - Neuro-ophthalmology
The authors present the findings of a prospective cohort study. Three hundred and five stroke survivors were recruited consecutively. The following exclusion criteria were applied; aphasia, cognitive impairment, visual inattention, ocular motor nerve palsy and neuromuscular disease. Fifty age-matched controls...
Screening for visual processing deficits in dementia
5 April 2022
| Claire Howard
|
EYE - Neuro-ophthalmology
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Dementia, cognitive impairment, screening test, visual deficits, visuospatial
The Queen Square Screening test for Visual Deficits (QS test) screens for changes in visual processing. It has never been formally validated as a single test. The test consists of a short booklet developed using remnant object and spatial perception...
Using optical coherence tomography angiography to detect MoyaMoya vasculopathy
5 April 2022
| Claire Howard
|
EYE - Neuro-ophthalmology
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Neuro-ophthalmology, moyamoya vasculopathy, optical coherence tomography angiography, retina
Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...
Where along the vergence pathway is affected by Parkinson’s Disease?
5 April 2022
| Lauren R Hepworth
|
EYE - Neuro-ophthalmology
The authors outlined three hypothesis for the effect Parkinson’s Disease has on blur- and disparity-driven vergence with reference to location within the vergence system that is affected to be tested in this prospective study. The study recruited 14 participants with...
G-CSF intravitreal injections for NAION: a pilot study
5 April 2022
| Su Young
|
EYE - Neuro-ophthalmology
|
Anterior ischemic optic neuropathy, Granulocyte colony-stimulating factor, Intravitreal injection, Neuroprotection, Optic atrophy
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...
Outcomes after surgery for INS
The purpose of this study was to detail clinical and electrophysical outcomes after extraocular muscle surgery in adults with infantile nystagmus syndrome (INS). This was a single centre prospective case series of 81 patients aged 18-72 years (mean 36); 63%...
