Cataract progression after Nd-YAG laser iridotomy in primary angle-closure suspect eyes
2 February 2024
| Jonathan Chan
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EYE - Glaucoma
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Angle, Clinical Trial, Glaucoma, Treatment Lasers, Vision
A total of 889 of eligible bilateral primary angle-closure suspect (PACS) patients were recruited from the Zhongshan Angle Closure Prevention Trial. One randomly selected eye received laser peripheral iridotomy (LPI), while the fellow remained untreated. Cataract was graded by the...
Detecting glaucoma with only OCT
3 April 2023
| Zhihang Cheng
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EYE - Glaucoma
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Glaucoma, OCT, Optical coherence tomography, Retinal ganglion cell layer, Retinal nerve fiber layer
In this review article, the authors describe a probability model based upon only OCT to detect glaucoma. They explain how normal anatomical variation can lead to false positives and applying a model to account for this improves specificity. The application...
Ocular hypertension following intravitreal steroid injections: a comparative study between triamcinolone-acetonide and dexamethasone-implant
3 April 2023
| Sofia Rokerya
|
EYE - Vitreo-Retinal
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Dexamethasone-implant, Glaucoma, Intravitreal steroid-induced ocular hypertension, Risk factors for steroid-induced ocular hypertension, Triamcinolone-acetonide
This was a retrospective observational study of steroid response following 1549 intravitreal steroid (TA and Dex) injections. One thousand and seventy-five eyes of 897 patients were reviewed. Glaucoma patients, glaucoma suspects, uveitis, trauma, and cases with less than one month...
Detecting apoptosis in retinal cells
1 February 2022
| Sofia Rokerya
|
EYE - Vitreo-Retinal
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Apoptosis, Glaucoma, Imaging, Neurodegeneration, Retina
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
A pulsatile pump in the TM, a new concept in trabecular outflow research
1 October 2021
| Zhihang Cheng
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EYE - Glaucoma
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Aqueous outflow pump, Elastance, Glaucoma, Intraocular pressure regulation, Pulsatile aqueous outflow, Schlemm's canal valves
This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...
Uveitis‐Glaucoma‐Hyphaemia syndrome retrospective case-control study
7 April 2021
| Kareem Waleed Alsaffarini
|
EYE - Glaucoma
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Uveitis-Glaucoma-Hyphaema syndrome, iris transillumination defects, malpositioned intraocular lens
The authors present the findings of a case-control study aiming to assess uveitis‐glaucoma‐hyphaemia (UGH) syndrome, focusing on the resolution, glaucoma development and risk factors. The authors compared three groups each containing 71 patients. Each group contained patients with UGH syndrome,...
A novel way to diagnose optic neuropathies using Bruch’s membrane opening
7 December 2020
| Claire Howard
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EYE - Neuro-ophthalmology
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Glaucomatous neuropathy, compressive optic neuropathy, minimal rim width, non-arteritic anterior ischaemic optic neuropathy, non-glaucomatous neuropathy
Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...
Glaucoma and capillary perfusion
1 August 2019
| Kurt Spiteri Cornish
|
EYE - Glaucoma
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Glaucoma, OCTA, field of vision, intraocular pressure, macula, optic nerve
Elevated IOP is important but not the sole factor responsible for retinal ganglion cell (RGC) death and optic nerve damage in glaucoma. There is increasing evidence that visual loss correlates with macular inner retinal thinning. A total of 148 eyes...
Low cost drainage device use in paediatric glaucoma
1 October 2018
| Jonathan Chan
|
EYE - Glaucoma
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Baerveldt, Childhood Glaucoma, Glaucoma Drainage Device
This is a prospective study from a tertiary referral centre from India of 34 eyes (31 patients) under 16 years with uncontrolled refractory glaucoma with medical treatment. A low cost glaucoma drainage device (GDD) – Aurolab aqueous drainage implant (ADDI),...
Resveratrol protects against steroid induced intraocular pressure
1 April 2016
| Graham Wallace
|
EYE - General
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Glaucoma, Intraocular pressure, Resveratrol, Retina, Steroid-induced, Trabecular meshwork
Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...
SS-OCT assessment of ITC after phacoemulsification
This is a multicentre randomised controlled trial of 22 patients with primary angle closure glaucoma with peripheral anterior synechia and peripheral primary angle closure glaucoma (PACG) with peripheral anterior synechia (PAS) detected by indentation gonioscopy was randomised into two groups....
Intracameral bevacizumab as an adjunct to trabeculectomy
This is a 12-month, prospective, randomised, double-masked, placebo-controlled trial of patients who were not controlled medically with open angle glaucoma and scheduled for a primary trabeculectomy. Patients were recruited and randomised during the period between April 2009 and November 2010....
