OCTA in angioid streaks
1 February 2019
| Saruban Pasu
|
EYE - Vitreo-Retinal
This paper reports on the optical coherence tomography angiography (OCTA) features of choroidal neovascularisation (CNV) secondary to angioid streaks and the ability to predict CNV activity. A total of 38 eyes of 19 patients were included in the study. Thirty...
Type 3 CNV and anti-VEGF
1 February 2019
| Saruban Pasu
|
EYE - Vitreo-Retinal
The purpose of the study was to determine the differences between aflibercept and ranibizumab in terms of their therapeutic efficacy in the treatment of Type 3 neovascularisation. The authors highlight that the dominant mechanism for Type 3 neovascularisation development is...
Cataract surgery in patients with Vogt-Koyanagi-Harada
1 February 2019
| Tasmin Berman
|
EYE - Vitreo-Retinal
This retrospective, interventional case series of 286 patients (408 eyes) assessed visual outcome and prognostic factors in patients with Vogt-Koyanagi-Harada (VKH) undergoing cataract surgery between September 2008 and December 2017. Two groups were reviewed. The first group (352 eyes) had...
Radiation maculopathy
1 December 2018
| Jonathan Chan
|
EYE - Vitreo-Retinal
This is a retrospective non-randomised study of 13 consecutive eyes of 13 patients affected by radiation maculopathy secondary to eye irradiation for primary uveal melanoma (Iodine-125 brachytherapy). All patients were treated with a single intravitreal 0.7mg dexamethasone implant and full...
Macular pigment and dark adaptation in older population with normal maculas
1 December 2018
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...
Effects of blood donation on the physiology of the eye
1 December 2018
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...
Ranibizumab safety in pregnancy
1 December 2018
| Sofia Rokerya
|
EYE - Vitreo-Retinal
Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...
OCTA and pigment epithelium detachments
1 December 2018
| Saruban Pasu
|
EYE - Vitreo-Retinal
Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...
2018 update on intravitreal injections
1 December 2018
| Sofia Rokerya
|
EYE - Vitreo-Retinal
In this review article the authors have highlighted the standardised and structured approach to intravitreal injections (IVI) by examining the recent evidence-based literature. IVI is the most commonly performed procedure worldwide with low potential risk of endophthalmitis. IOP spikes are...
Incidence and risk factors of ocular hypertension following PPV and SOI
1 December 2018
| Sofia Rokerya
|
EYE - Vitreo-Retinal
In this prospective, interventional study the authors evaluated the risk factors for elevated intraocular pressure (IOP) after pars plana vitrectomy (PPV) with silicone oil injection (SOI). This study included 254 eyes of 254 patients, with a mean age of 55.33...
Reduction of severe visual loss and complications following IAC for RB
1 October 2018
| Jonathan Chan
|
EYE - Vitreo-Retinal
This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...
PRN Ranibizumab verses continuous aflibercept in UK clinical practice
1 October 2018
| Jonathan Chan
|
EYE - Vitreo-Retinal
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...
