Where along the vergence pathway is affected by Parkinson’s Disease?
5 April 2022
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors outlined three hypothesis for the effect Parkinson’s Disease has on blur- and disparity-driven vergence with reference to location within the vergence system that is affected to be tested in this prospective study. The study recruited 14 participants with...
G-CSF intravitreal injections for NAION: a pilot study
5 April 2022
| Su Young
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EYE - Neuro-ophthalmology
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Anterior ischemic optic neuropathy, Granulocyte colony-stimulating factor, Intravitreal injection, Neuroprotection, Optic atrophy
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...
Long-term use of botulinum toxin for hemifacial spasm and blepharospasm
1 February 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Botulinum neurotoxin, benign essential blepharospasm, hemifacial spasm, tolerance
The authors conducted a retrospective review of clinical / procedure documentation for consecutive blepharospasm (BEB) and hemifacial spasm (HFS) patients undergoing treatment with onabotulinum toxin A (Botox) in one clinic setting over the past 20 years. They report on the...
Case reports of ‘ictal lid saccades’ and ‘ictal blinks’
The authors present two cases of lid movements with discrete physiology and propose the terms ‘ictal lid saccades’ and ‘ictal blink’ to describe the movements seen. These two types of lid movement, blinks and saccades, have discrete kinematic properties and...
Lagophthalmos as a potential complication of COVID-19
1 February 2022
| Claire Howard
|
EYE - Neuro-ophthalmology, EYE - General
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Bell’s palsy, COVID-19, anosmia, coronavirus, Lagophthalmos
Lagophthalmos is a condition associated with the inability to close the eyelids effectively, with the main cause being facial nerve palsy. The authors aimed to investigate whether lagophthalmos was associated with coronavirus infection (COVID-19) by comparing patients diagnosed with lagophthalmos...
A survey of neuro-ophthalmologists on use of corticosteroids in giant cell arteritis
1 December 2021
| Claire Howard
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EYE - Neuro-ophthalmology
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Giant Cell Arteritis, corticosteroid, dosage, vasculitis, vision Loss
While corticosteroids are the mainstay of treatment in giant cell arteritis (GCA), the type, dose, route and duration of treatment remains controversial. The authors surveyed 180 neuro-ophthalmologists on their use of this treatment via email in a two-month period. Results...
A retrospective medical notes review in patients with poor vision due to NAION
1 December 2021
| Claire Howard
|
EYE - Neuro-ophthalmology
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Non-arteritic anterior ischaemic optic neuropathy, NAION, severe visual loss, visual acuity
Very severe visual loss (hand movements or less) is typical of arteritic anterior ischaemic optic neuropathy (AION) and relatively rare in non-arteritic AION (NAION). This study aimed to report the frequency of very poor visual acuity (VA) in NAION. The...
Long-standing flattening effects on the globe following spaceflight
1 December 2021
| Claire Howard
|
EYE - Neuro-ophthalmology
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SANS, astronaut, hyperopic shift, international space station (ISS), long-duration space flight (LDSF), visual changes
Posterior globe flattening has been well-documented in astronauts both during and after long-duration spaceflight (LDSF). This globe flattening is thought to be due to the disc centred anterior forces created by elevated volume and / or pressure within the optic...
A case presentation of morning glory disc anomaly and peripapillary staphyloma
1 December 2021
| Claire Howard
|
EYE - Neuro-ophthalmology
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Morning glory disc anomaly, amblyopia, contractile staphyloma, esotropia
The purpose of this paper is to present a case of an 18-month-old girl initially presenting with strabismus. Fixation of the affected eye was intermittent with a relative afferent pupillary defect. A fundus photography of the affected left eye showed...
Differences between ages and onset in functional network changes associated with reading Braille
1 December 2021
| Claire Howard
|
EYE - Neuro-ophthalmology
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Braille, early blind, fMRI, functional connectivity, late blind, voxel-based morphometry
Visual impairment affects learning ability, speed and accuracy required for reading, writing and learning memory in terms of educational performance. Braille training requires decoding of simple dots into meaningful words and sentences. The objectives of this study were to evaluate...
Unusual case presentation of arteritic anterior ischaemic optic neuropathy
1 December 2021
| Claire Howard
|
EYE - Neuro-ophthalmology
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Arteritic anterior ischaemic, optic neuropathy, polyangiitis overlap syndrome
The authors present a single case of an 84-year-old man with arteritic anterior ischaemic optic neuropathy, but with unusual features on temporal artery biopsy. He presented with a three-day history of sudden onset of loss of vision in his right...
Detection of post stroke visual impairment in variety of cohorts
1 December 2021
| Claire Howard
|
EYE - Neuro-ophthalmology
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Reproducible, Stroke, incidence, prevalence, vision
The Impact of Visual Impairment after Stroke (IVIS) study introduced a standardised vision assessment protocol across three acute stroke units in the northwest of England, with a similar demographic population (predominantly white British). The study reported similar rates of visual...
