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Treat-and-extend regimen in treatment of patients with type 3 neovascularisation
Type 3 neovascularisation, also known as retinal angiomatous proliferation is a distinct subtype of neovascular AMD characterised by intraretinal neovascularisation. This retrospective study included 17 eyes diagnosed with type 3 neovascularisation who were changed from pro-re-nata (PRN) based treatment regime...
Intravitreal Ziv-Aflibercept: safety analysis
Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...
Biometric changes in phakic eyes over time
This was a single-centre retrospective cohort study of patients who attended a ‘two-stop’ preassessment clinic for consideration of cataract surgery between November 2002 and March 2015. Four biometric measurements were recorded: axial length, horizontal (K1) readings, vertical (K2) readings and...
Effects of ‘inverted U method’ Nd:YAG laser posterior capsulotomy on anterior segment and IOL tilt
The study aimed to investigate the effects of the ‘inverted U method’ Nd:YAG laser posterior capsulotomy on anterior segment parameters, decentration and tilt of intraocular lens (IOLs) and visual acuity in 76 patients with posterior capsular opacification (PCO) after previous...
The effects of ab-interno XEN gel implantation on postural IOP elevations
The study involved 18 patients with XEN gel implants, 30 patients who had trabeculectomy, and 30 medically managed glaucoma patients. All patients in XEN gel implant and trabeculectomy groups had at least 11 months of follow-up following successful surgery resulting...
Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG
This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...
The effects of anti-VEGF therapy for NvAMD on retinal vasculature
This retrospective consecutive case series examined 54 eyes of 54 treatment-naïve neovascular age-related macular degeneration (N-AMD) patients. Thirty-three eyes received intravitreal aflibercept injections, and 21 eyes received intravitreal ranibizumab injections with unaffected fellow eyes (54 eyes) as controls. All image...
Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus
This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...
Transcanalicular diode laser-assisted DCR: success rates and factors for success
This study aimed to evaluate the success rates of transcanalicular diode laser-assisted dacryocystorhinostomy (TCL-DCR) during three years of follow-up and to find clinical factors that influence surgical outcomes. Major outcomes were defined as a patent neo-ostium tested by irrigation (anatomical...
OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema
This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....
Does lower eyelid entropion repair alter corneal topography?
The authors aimed to analyse the corneal morphology before and after advancement of posterior lower eyelid retractors (LERs) alone or in combination with a lateral tarsal strip (LTS) for lower eyelid involutional entropion. Retrospective analysis of 24 consecutive elderly patients...
