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Sebaceous gland carcinoma
This is a review of 241 patients diagnosed with periocular sebaceous gland carcinoma which investigates whether age at presentation influences either the clinical presentation or the outcomes of treatment. Twelve percent of patients were classified as young (<40 years old),...
How a paediatric population presented with diplopia
The authors present the results of a retrospective records review of 244 children presenting with diplopia over a three-year period. The majority of cases presented to paediatric ophthalmology clinic; other routes of presentation included eye casualty, neuro-ophthalmology or another eye...
Adjuvant radiotherapy in orbital malignancy
This is a retrospective review of high dose volumetric modulated arc radiotherapy (VMAT) for adjuvant treatment of patients with orbital malignancy who had already undergone local excision or exenteration. VMAT differs from conventional external beam radiotherapy in that it is...
Profile of paediatric cranial nerve palsies
The purpose of this study was to retrospectively assess the aetiology of paediatric ocular cranial nerve palsies (CNP) using neuro-ophthalmic data from three hospitals. The study included 1263 patients aged <18 years suspected of having strabismus, from January 1999 to...
Ocular adnexal mantle cell lymphoma
In this study the authors compare primary ocular adnexal (OA) mantle cell lymphoma (MCL) with initially systemic MCL occurring over a 30-year period. MCL is a rare form of lymphoma accounting for 5-11% of OA lymphomas and therefore knowledge of...
Features of childhood cases of sixth nerve palsy
Based on limited information available for cranial nerve palsies in children, the authors aimed to collect data on new onset paediatric sixth nerve palsies in a UK population. This was a retrospective study over 10 years for children aged <18...Choroidal melanoma – breaking bad news
Case report A 55-year-old Caucasian female presented to her general practitioner with a three-month history of headaches and worsening blurred vision in the left eye. On further close questioning, she reported no eye pain, intermittent floaters and flashes of light...
Tutopatch® in surgical management of third nerve palsy
his study evaluates the benefit of using Tutopatch® to elongate the extraocular muscles in patients with third nerve palsy who have residual strabismus after unsuccessful surgery and no other surgical options considered to be appropriate. The study included nine patients...
Reduction of severe visual loss and complications following IAC for RB
This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...
Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma
The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...
A mouse model for uveal melanoma
Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...
