This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.  Read our Cookies Policy.
Close
Eye News
  • Features
    • Close
    • Features
    • Allied Professions
    • Humanitarian
    • Interviews
    • AI & Oculomics
    • Ophthalmology
    • Optometry
    • Podcast videos
    • Supplements
  • Education
    • Close
    • Education
    • Learning Curve
    • Quiz
    • Top Tips
    • Trainees
    • Medico-Legal
    • The Truth Behind The Headlines
    • Case Reports
    • Pete's Bogus Journey
  • Reviews
    • Close
    • Reviews
    • Book Reviews
    • Journal Reviews
    • What's trending?
    • Tech Reviews
    • My Top Five
    • The Culture Section
  • Events
  • News
  • Product Guide
  • Industry News
  • Contact us
    • Close
    • Contact us
    • Write for Eye News
  • Home
  • Reviews
  • Journal Reviews
  • Adjuvant radiotherapy in orbital malignancy

Adjuvant radiotherapy in orbital malignancy
Reviewed by James Hsuan

1 June 2022 | James Hsuan | EYE - Oculoplastic, EYE - Orbit
Share This

This is a retrospective review of high dose volumetric modulated arc radiotherapy (VMAT) for adjuvant treatment of patients with orbital malignancy who had already undergone local excision or exenteration. VMAT differs from conventional external beam radiotherapy in that it is a form of intensity modulated treatment where portions of the beam are blocked, and delivered in an arc or series of arcs rather than in a square or rectangular shaped beam. This allows better focusing of the beam on the target areas whilst minimising exposure to other critical structures. Eighty-four patients comprising 48 local excisions and 36 exenterations underwent VMAT with a mean dose of 65Gy. After a mean follow-up of 18 months, there was no change in visual acuity in the local excision group, and only single cases each of bacterial keratitis, corneal opacification, radiation retinopathy, radiation optic neuropathy and cicatricial entropion. Severe dry eye occurred in three patients. The incidence of these complications was far lower than that reported with conventional external beam radiotherapy. The study suggests this is a treatment with fewer serious side-effects, but the follow-up may be too short for some later complications and there was no data on tumour recurrence rates.

Ocular, orbital, and adnexal toxicity with high-dose volumetric modulated arc radiation therapy for orbital malignancies.
Garcia GA, Charlson ES, Kolseth C, et al.
OPHTHALMIC AND PLASTIC RECONSTRUCTIVE SURGERY
2022;38:132-7.
Share This
James Hsuan
CONTRIBUTOR
James Hsuan

Aintree University Hospital, Liverpool, UK.

View Full Profile
Specialty
  • EYE - Cataract
  • EYE - Cornea
  • EYE - General
  • EYE - Glaucoma
  • EYE - Neuro-ophthalmology
  • EYE - Oculoplastic
  • EYE - Oncology
  • EYE - Orbit
  • EYE - Paediatrics
  • EYE - Pathology
  • EYE - Refractive
  • EYE - Strabismus
  • EYE - Vitreo-Retinal
Archive
  • 2025
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013

Top Of Page

9 Gayfield Square, 
Edinburgh EH1 3NT, UK.

Call: +44 (0)131 557 4184
www.pinpoint-scotland.com

WEBSITE DETAILS
  • Cookie Policy
  • Data Protection Notice
  • Privacy Policy
  • Terms and Conditions
ABOUT US
  • Who we are
  • Register
  • Contact us
  • Contributors
  • Company Awards
DIGITAL ISSUES/GUIDELINES
  • Digital issues - Library
  • Supplements - Library
  • Guidelines
Accreditations
IPSO_FLAG_TEAL 2025.png cpdcertified.png

Pinpoint Scotland Ltd (Registered in Scotland No. SC068684) | © 2025 - Website by Gecko Agency