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Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

The management of antiplatelets and anticoagulation in elective ophthalmic surgery

1 April 2016 | | Orbit, Oculoplastics
Clinical scenario: A 57-year-old gentleman who is scheduled to have Mohs micrographic surgery and reconstruction for a medial canthal basel cell carcinoma (BCC) has been started on aspirin and clopidogrel following a coronary stent three weeks ago. Does the antiplatelet...

ESASO Course Series (Volume 2): Surgical Retina

1 June 2014 | | Ophthalmology, Retina / Uvea / Vitreous
This book comprises details of symposia / seminars on surgical aspects of retina presented by renowned authorities in ophthalmology from all over the world during ESASOS (European School for Advanced Studies in Ophthalmology) academic activities, which are mentioned in a...

Ophthalmic mentors: Professor Carrie MacEwen

1 February 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Caroline (Carrie) MacEwen is a Consultant Ophthalmologist at Ninewells Hospital and Medical School, Dundee, and Head of the Ophthalmology Department at the University of Dundee (Honorary Professor). She trained in Glasgow, Dundee and London. Carrie took over as President of...

A patient report of pseudoxanthoma elasticum, angioid streaks and choroidal neovascularisation

1 October 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Angioid streaks (AS) on their own do not cause many problems, with the majority of patients remaining asymptomatic [1]. However, once choroidal neovascularisation (CNV) occurs, the visual prognosis of the patient rapidly declines [2]. Treatment is imperative to try and...

Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management

1 December 2016 | | Retina / Uvea / Vitreous
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...

Neurofibromatosis type 2 – diagnosis, features and MDT approach

1 December 2021 | | Ophthalmology, Orbit, Retina / Uvea / Vitreous, Cataract and Refractive
NF2 is a genetic condition caused by mutation in a single gene (NF2 gene) on chromosome 22. The NF2 gene provides instructions to produce a protein called merlin, also known as schwannomin. This protein functions as a tumour suppressor, preventing...

Patient changes eye colour permanently and has brighter and whiter looking eyes

1 December 2017 | Cornea / External Eye Disease, Ophthalmology
In this new series, Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are scientific reality and which are ‘fake news’. Headline: Patient changes eye colour permanently and has brighter and whiter looking eyes If...

A near miss

1 February 2019 | | Ophthalmology, Retina / Uvea / Vitreous
A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...

The past and the future for paediatric ophthalmology

1 June 2018 | | Paediatric Ophthalmology / Strabismus
The past 25 years have seen remarkable advances in clinical eye care for children in the UK. This has led to both improved outcomes and better patient and family experiences. There have been substantial changes to patient pathways, major advances...

A paradigm shift in the way we approach cataract surgery

1 February 2015 | | Cataract and Refractive
Cataract surgery is the most common elective surgical procedure in the UK [1], with in the region of 350,000 cases being conducted each year. With an ageing population, this figure will only continue to rise over time. Cataract surgery is...

Case series of toxic anterior segment syndrome

1 August 2019 | | Ophthalmology, Cataract and Refractive
Herein we report two cases of toxic anterior segment syndrome (TASS) following uneventful cataract surgery. Both patients presented 24 hours after their uneventful operations with painless blurred vision in the operated eye. The inflammatory reaction was controlled successfully with an...