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Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Sharing best practice and landmark evidence in glaucoma care

Evolving technology, best practice and landmark evidence in glaucoma care were reviewed by an international expert faculty in session presentations and debates during the 11th Moorfields International Glaucoma Symposium 2019. The authors were meeting chairs and provide an overview of...

How a paediatric population presented with diplopia

The authors present the results of a retrospective records review of 244 children presenting with diplopia over a three-year period. The majority of cases presented to paediatric ophthalmology clinic; other routes of presentation included eye casualty, neuro-ophthalmology or another eye...

Visual disturbance heralding stroke: are we seeing the signs in time?

Isolated visual symptoms may be an early presenting feature of stroke, and timely recognition of such atypical cases is important because treatment for stroke has a limited time-window of efficacy. Stroke occurs in approximately 150,000 people per year in the...

Disseminated cutaneous zoster – a masquerade

Reactivation of varicella zoster infection in the elderly commonly presents to ophthalmologists as herpes zoster ophthalmicus (HZO), affecting the Va trigeminal dermatome. In patients with impaired immunity, zoster infection occurs with increased severity and may be complicated by visceral and...

Refractive changes over time for fully accom esotropia

The purpose of this study was to determine refractive error changes across time and to define factors contributing to decompensation in patients with fully accomodative esotropia (FAET). This was a retrospective study of 223 patients with a mean age at...

World Diabetes Day workshop highlights the importance of education to protect the sight of people living with diabetes

Health professionals from all over the world came together to mark World Diabetes Day on 14 November 2022 through an online workshop celebrating progress in development of diabetic retinopathy (DR) services in low-and middle-income countries (LMICs).

Demyelinating optic neuropathy

Introduction Optic neuritis (ON) is an inflammatory process affecting the optic nerve. After glaucoma, it is the most common optic neuropathy affecting patients under the age of 50. The usual presentation of typical ON is unilateral subacute loss of vision...

Understanding and confronting bacterial endophthalmitis

Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...

Changing the post cataract surgery review pathway – is patient safety compromised?

Cataract surgery continues to be the most commonly performed elective surgical procedure in the UK, with an annual rate of approximately 4150/100,000 people over the age of 65 accounting for a significant proportion of the surgical workload of most ophthalmologists...

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Sight Sciences OMNI® Masterclass

The program focuses on real-world experience of the implant-free MIGS procedure from two of the UK’s leading Glaucoma specialists. Following presentations covering combined canaloplasty and trabeculotomy, attendees will be given the chance to take part in a dry-lab with support...