You searched for "inflammation"
Intraocular Inflammation
1 August 2018
| Jaya Myneni
|
Ophthalmology
Intraocular Inflammation is an encyclopedic treatise on uveitis. The editors have invited several experts in the field to author different chapters and provide the reader with an excellent repository of knowledge, experience and evidence on the subject. The approach to...
Conjunctival inflammation in glaucoma patients
1 April 2015
| Khadijah Basheer
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EYE - Glaucoma
Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...
The role of inflammation in the pathophysiology of DMO
1 February 2016
| Fiona Harris, Spyridon Chalkiadakis, Simon Taylor (Prof)
|
EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...
Bisphosphonates can cause orbital inflammation
1 April 2016
| Claire Howard
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EYE - Neuro-ophthalmology
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Bisphosphonate, complication, orbital inflammation, orbital inflammatory syndrome, side effect, zolendronate
The authors describe four patients with bisphosphonate induced orbital inflammation and review a further 25 cases in the literature. Intravenous zoledronate was the most common precipitant (76% of cases) with the mean time until onset of inflammation being three days...
Grading of ocular inflammation in uveitis: an overview
1 February 2016
| Rod McNeil
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EYE - Vitreo-Retinal
Anterior uveitis is the commonest form of uveitis, which can lead to severe morbidity if not treated appropriately [1]. Data from general ophthalmology practices suggest around 90% of uveitis encountered by comprehensive ophthalmologists is anterior uveitis [2]. Intermediate (vitreous), posterior...
Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
1 June 2018
| Graham Wallace
|
Retina / Uvea / Vitreous
|
Adipocytokine, Angiopoietin-like protein-4 (ANGPTL-4), Diabetic retinopathy (DR), Hypoxia inducible factor-1 alpha (HIF-1α), Inflammation, Profilin-1
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Differentiating orbital cellulitis from non-specific orbital inflammation
4 December 2023
| Hetvi Bhatt
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Oculoplastics, Orbit
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C-Reactive protein, Non-specific orbital inflammation, inflammatory markers, orbital cellulitis, white-cell count
This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...
Effect of cataract surgery on inflammation control and vision in uveitis patients
1 June 2019
| Ivan Yip
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EYE - Cataract, EYE - Refractive
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cataract surgery, phacoemulsification, uveitis, vision impairment
This retrospective longitudinal study from Moorfields, London, UK compared uveitis recurrence rates and vision loss in 309 eyes of uveitis patients post cataract surgery to 300 control uveitis patients. Cataract is a common complication associated with uveitis and leads to...
International Ocular Inflammation Society (IOIS) Congress September 2023 in a sweltering Berlin
14 September 2023
| Nima John Ghadiri
|
IOIS, Berlin, Conference, Report, Event, ocular inflammation, Hagar Ibrahim, Dhanach Dhirachaikulpanich, Nima Ghadiri
Approaching its 40th year, IOIS remains focused on advancing research and knowledge-sharing around ocular inflammatory diseases.
IOIS (International Ocular Inflammation Society) Congress
6 September 2023
-9 September 2023
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Retina / Uvea / Vitreous, Ophthalmology
CD40L activation of human RPE cells
1 August 2018
| Graham Wallace
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Retina / Uvea / Vitreous
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AMD, Age-related macular degeneration, CD40L, IL-1β, Inflammasome, MCP-1, RPE, Retinal pigment epithelium
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...
