You searched for "epithelium"

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Principles of management

Whatever section of pathology is to blame and wherever it strikes, the aim of treatment is always the same. Find the cause if you can. Establish the effects of the cause. Halt the pathological process if you can. Reverse its...

Platelet rich fibrin membrane for descemetocele

This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...

Cornea teaching techniques: one cornea donor tissue for two purposes

There is a national shortage in the UK in corneal graft material [1,2]. The majority (69%) of corneal transplants in the UK are partial thickness, with 35% being Descemet membrane endothelial keratoplasty (DMEK) [2]. During the preparation of the donor...

Feb/Mar 2014 Quiz 2

History A 65-year-old lady presented with a ten year history of nonspecific visual disturbance and mild symptoms of dry eyes. Questioning revealed progressive nyctalopia. Previous medical history of note included Crohn’s disease requiring two bowel resections including small intestine. Figure...

Herpes zoster ophthalmicus: a clinician’s perspective

Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

Reduced blood flow and age-related macular degeneration

This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...

Microperimetry of subretinal drusenoid deposits

Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Laser pointer maculopathy

The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...

Customised corneal crosslinking with supplemental oxygen

In this prospective interventional case series, the authors investigate using supplemental oxygen delivery during epithelium-on corneal crosslinking (CXL) with specially designed oxygen delivery goggles. Twenty-seven eyes of 24 patients underwent epi-on CXL with Riboflavin and Ultraviolet-A irradiation. At six months...

A paradigm shift: re-defining success in retinal detachment repair

The authors describe in this review article that functional outcomes vary with surgical technique for retinal detachment repair. Traditional definitions of surgical success have been shifted due to advances in imaging techniques. Assessment of the integrity of retinal reattachment including...

Role of fundus autofluorescence patterns and baseline atrophy area on geographic atrophy progression

Central geographic atrophy (GA) is one of the morphological sub types of late-stage macular degeneration. The natural course of the disease is characterised by expanding areas of macular atrophy, which cause absolute scotoma. Fundus autofluorescence (FAF) is derived from lipofuscin...