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Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

PACK-crosslinking for infectious keratitis

Corneal cross-linking with riboflavin and UV-A light (CXL) is a technology that has been initially developed to treat corneal ectatic disorders [1]. Its effect in stabilising diseases such as keratoconus was reported in numerous trials with excellent long-term outcomes and...

Understanding amniotic membrane grafts

Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

Chemical injury

You are the on-call ophthalmologist. You receive a call from A&E regarding a 45-year-old man who sustained a chemical injury. He was mixing some cement, when a small amount entered his left eye. He was not wearing any protective goggles....

Stem cell transplantation and pterygium surgery

Pterygium is a benign, fibrovascular overgrowth of bulbar conjunctiva extending onto the cornea and has been associated with ultraviolet (UV) light exposure. The prevalence of pterygium worldwide varies between geographical zones but has been reported to range between three and...

Topography-guided photorefractive keratectomy in the treatment of corneal scarring

This study reports the outcome of topography-guided photorefractive keratectomy (TG-PRK) in the treatment of patients with corneal scarring. A retrospective case series including six eyes of six patients with corneal scarring and irregular astigmatism who underwent topography guided PRK. The...

Patients use their own blood to treat dry eye symptoms

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’? Headline: Patients use their own blood to treat dry eye symptoms Grossman first described the technique of...

Surgical options for the treatment of hyperopia

The modern refractive surgeon has a variety of options available to treat patients with hyperopia who wish to be independent of spectacles and contact lenses. Unlike in low myopia where presbyopic patients may have the ability to see well for...

Choosing a subspecialty

It is quite worrying how many registrars reach the final years of training without choosing a subspecialty. Sometimes this is because they love everything and cannot countenance giving any of it up, but more commonly this is due to various...

Results of corneal cross-linking in very steep corneas

Corneal cross-linking (CXL) has been shown to be a safe and valid treatment option for progressive keratoconus and have shown an arrest of progression with a low failure rate of 0% to 2.8% in mild to moderate keratoconus. A Kmax...

Dec/Jan 2016 Quiz

History A 40-year-old swimming instructor undergoes an enucleation for a blind painful eye. There is a history of soft contact lens wear. She has had a corneal abscess and corneal graft procedures in the past. Questions 1. What does this...

Topical doxycycline for corneal neovascularisation

Six eyes with corneal vascularisation were treated with 1% topical doxycycline, four times a day for three weeks. The patients were reviewed at various intervals over a period of one year. The eyes selected had neovascularisation secondary to a variety...