You searched for "RPE"

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DMEK vs. UT-DSAEK: has the debate been finally concluded?

In recent years the surgical treatment of corneal endothelial dystrophy has progressed tremendously. Descemet’s membrane endothelial keratoplasty (DMEK) is the newest iteration in the line of rapid surgical advances that has taken place. However, the previously accepted gold standard prior...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Assessing everyday visual function in dry AMD – what matters to the person?

Age-related macular degeneration (AMD) is the primary cause of blindness in the developed world and is accountable for more than one half of sight impairment registrations within England and Wales [1]. AMD is prevalent in people aged 60 years and...

Microdroplet and splatter contamination during phacoemulsification in COVID-19 era

Half a millilitre of fluorescein was incorporated into 400ml of balanced salt solution to identify microdroplet and splatter from phacoemulsification to simulate possible COVID-19 contamination. Five porcine eyes were mounted to an ophthalmic mannequin head and two surgeons (height 189cm,...

Optical practices to continue to provide urgent and essential care

The UK Government has now published further guidance clarifying that opticians are exempt from the general requirement for retail businesses and premises to close. Optical practices may therefore continue to provide urgent and essential eye care to the extent that they can, including remote care, while managing COVID-19 risk to keep patients, staff and the public as safe as possible.

Ophthalmology in the COVID-19 pandemic

The novel coronavirus pandemic has affected the whole world and forced all of us to think of new ways to manage our day to day personal as well as professional life. I am not going to talk about the clinical...

Optimising an acute eye service in the current COVID-19 crisis

With the current global pandemic of COVID-19 we have all had to redesign and reorganise our normal working practices. Non-urgent hospital work has been postponed to allow redistribution of resources, redeployment of hospital staff and to reduce the risk of...

Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

Is patient masking leading to an increase in post-op infection after eyelid surgery?

Due to the COVID-19 pandemic, the use of facemasks or face coverings in the clinical setting has become necessary. It is important to recognise that facemasks can be a source of infection after eye surgery and consider ways to minimise...

Providing primary eyecare services during a global pandemic: the new normal

It would be fair to say that 2020 hasn’t quite turned out to be the year that anyone predicted. Living with a global pandemic has become our reality and we are having to get used to many aspects of our...

Novel changes during COVID-19 – transforming a walk-in Eye Casualty to a telephone triage service

With the current pandemic climate due to COVID-19, out of the norm approaches have been adopted in different hospitals across the UK to ensure patient safety. At our Eye Casualty (EC) department at Northampton General Hospital (NGH), we felt the...

Blame the lens – not its position – in refractive surprise

Aetiology of postoperative refractive surprise Weber coined the term “wrong eye, wrong intraocular lens, wrong patient” in 2008 as an aide memoir of major factors believed to underlie refractive surprise – defined as a significant unintended difference between dioptric refraction...