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Meta-analysis of HLA B27 associated acute anterior uveitis

A literature-based meta-analysis was carried out to look at the various clinical features associated with HLA- B27 acute anterior uveitis (AAU). After an extensive search of literature for HLA B27 uveitis was conducted, 735 results were obtained. Twenty-nine articles were...

HLA-B27 anterior uveitis

HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...

The inflammatory side-effect of Brimonidine

Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...

Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis

This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....

High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis

This is a retrospective study from Auckland over a 10-year period. A total of 188 eyes of 139 subjects with either ocular hypertension (OH) or uveitic glaucoma (UG) were included for analysis with a mean follow up of 9.9 years....

High rate of conversion from ocular hypertension (OH) to glaucoma (UG) in subjects with uveitis

This is a retrospective study from Auckland over a 10-year period including 188 eyes of 139 subjects with either OH or UG and were included for analysis with a mean follow-up of 9.9 years. The most common uveitis causes were...

Uveitic glaucoma

The purpose of this retrospective study from two tertiary Institutions in Israel over a period of 13 years, is to present the long-term outcomes of uveitic glaucoma and to identify risk factors for progression. The study included 34 patients (53...

Sharing best practice and landmark evidence in glaucoma care

Evolving technology, best practice and landmark evidence in glaucoma care were reviewed by an international expert faculty in session presentations and debates during the 11th Moorfields International Glaucoma Symposium 2019. The authors were meeting chairs and provide an overview of...

Doctor at large

“In 1930, the Republican-controlled House of Representatives, in an effort to alleviate the effects of the… Anyone? Anyone?... the Great Depression, passed the… Anyone? Anyone? The tariff bill? The Hawley-Smoot Tariff Act? Which, anyone…?” In this memorable scene, the monotonous...

Certifying patients as visually impaired: the start of a journey

In March 2017 there were 290,475 people registered as either visually impaired or severely visually impaired in the UK [1]. Patients registered as sight impaired benefit from financial support as well as practical help. Practical help is provided by social...

The future of SLT?

For Feb/Mar 2024, we are looking at a recently released laser machine to perform direct SLT – selective laser trabeculoplasty (DSLT). Although SLT is well known, DSLT is sufficiently novel that a brief description is a good place to start....

Persistence of Ebola virus in ocular fluid during convalescence

The most recent Ebola outbreak has infected over 26,300 patients, but also resulted in the highest number of survivors in history. Uveitis has been described during the convalescent period, but Varkey and colleagues report, for the first time, finding viable...