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Under pressure: a tool to aid the non-ophthalmic practitioner in the timely management of acute angle closure
Acute angle closure is a true ophthalmic emergency that mandates timely diagnosis and treatment. The priority in initial management is to lower the intraocular pressure in an expeditious matter using medical treatments. The risk of irreversible glaucomatous optic neuropathy is...
Sustained elevation of extracellular ATP in chronic glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
A case series of acquired esotropia in cerebellar disease
Acquired esotropia in cerebellar disease is well described but under-recognised. The pathogenesis of cerebellar esotropia is controversial. It is suggested it may be a result of disruption to central vestibular pathways. This article reports a case series of seven adults...
An unusual case report of bilateral abducens paralysis
In this case report a nine-year-old girl develops bilateral abducens nerve paralysis, caused by vertebrobasilar dolichoectasia. Vertebrobasilar dolichoectasia is characterised by dilation, tortuosity and marked elongation of the vertebral and basilar arteries. Clinical findings result from the compression and displacement...
Investigating MOG-IgG as a cause for optic perineuritis
Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...
Sjogren’s syndrome in association with ophthalmoplegia
This is a case report of a 28-year-old female complaining of horizontal and vertical diplopia with inability to move her right eye and sudden onset right ptosis. She complained of retro-orbital pain with headache and a foreign body sensation in...
Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis
This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....
Narrative review of opsoclonus myoclonus ataxia syndrome following COVID-19
Opsoclonus myoclonus syndrome (OMS) / opsoclonus myoclonus ataxia syndrome (OMAS) is a rare central nervous system manifestation of COVID-19, but an increasing number of articles have reported patients in whom COVID-19 was complicated by OMS / OMAS. This narrative review...
Single case report of horizontal gaze paresis due to medial pontine haemorrhage
The authors report a single case (80-year-old female) of bilateral horizontal conjugate gaze palsy due to a dorsal median pontine haemorrhage. The patient presented with skew deviation, bilateral horizontal conjugate gaze palsy, vertical gaze palsy, ipsilateral lower motor neuron facial...
Comprehensive review of inherited retinal diseases
The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...Bilateral eye pain after contact lens wear: an inadvertent case of chemical eye injury
Introduction There are around 4.1 million contact lens wearers in the UK [1]. While the vast majority of them do not experience any complications, over the past years there have been cases of acanthamoeba keratitis and multiple retained contact lenses...
