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Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | EYE - Vitreo-Retinal, EYE - General
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Blind: Chris McCausland

4 February 2025 | | EYE - Vitreo-Retinal
In the busy, stressful lives that many of us lead, a good way to unwind in the evenings is to watch one of the celebrity panel TV shows such as Would I Lie To You? or Have I Got News...

Quiz Dec/Jan 2023

1 December 2022 | | EYE - General
History A 35-year-old female presented to the emergency eye clinic with an acutely red, painful, photophobic left eye. She was a contact lens-wearer but denied swimming, showering, or sleeping in her lenses. She resided on a farm and worked as...

Melanocytoma of the optic disc

1 June 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Melanocytoma is a heavily pigmented lesion, composed of melanocytes and is a variant of melanocytic naevus. It classically occurs at the optic disc and is usually benign, static and asymptomatic. However, it can occasionally grow and invade the retina or...

Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

4 December 2023 | | EYE - Neuro-ophthalmology
An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...

The madarosis mystery: unravelling the clues to a host of health issues

4 October 2023 | | EYE - Cornea
Eyelash madarosis is a medical condition characterised by the loss of eyelashes caused by the destruction of hair follicles. It can range from a few missing lashes to a complete absence of lashes on the eyelids. This condition can be...

Useful and controversial apps and services

1 October 2018 | | EYE - General
These apps and web services are not specifically ophthalmic but hopefully of interest. Office Lens Delegates take pictures of presentation slides at conferences quite frequently. If this is something you do, have a look at the ‘Office Lens’ app. This...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

1 October 2014 | | EYE - Cornea
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Leading North London eye clinic appoints retina expert to treat growing ‘epidemic’ of patients living with myopia

21 November 2023 | My-iClinic, myopia, Yvonne Luo, vitrectomy, floaters
Leading independent eye hospital based in Finchley, My-iClinic, has welcomed Consultant Ophthalmologist, Ms Yvonne Luo, to its growing team of specialists.

Toxic nutritional optic neuropathy (TON)

2 August 2022 | | EYE - General
Toxic optic neuropathy are a group of conditions manifested by reduction of visual functions secondary to damage to the anterior visual pathways from exposure to a toxin. The implicated toxin could be work-based, food or drink related, or iatrogenic medication....

The results of the last survey Jun23

5 June 2023 | | EYE - General
*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. I continue...

COMPlog – Electronic visual lane software

4 February 2021 | | EYE - General
COMPlog is software designed to replace physical Snellen and LogMAR charts. We have been using COMPlog since 2017 in the unit where I work. Some readers may find our experience, and reasons for choosing this product, interesting. This article is...