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Effectiveness of supramaximal horizontal surgery for third nerve palsy

The purpose of this study was to present the outcomes and progress of third nerve palsy cases after supra-maximal recession / resection. The aim is for an initial overcorrection of 15-25PD at day one. This was a retrospective study of...

Use of telemedicine within adult strabismus management

The aim of this survey was to assess the practice preferences in the management of adult strabismus among the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) committee members. A 27-question multiple-choice questionnaire was sent to 19 ophthalmologists on AAPOS...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Recommendation for wide angle fluorescein angiography to diagnose FEVR in NEDSDV

Neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV) is a genetic disease described in 2012 associated with variants in the CTNNB1 gene which encodes beta-catenin. Characteristics include strabismus, reduced visual acuity and familial exudative retinopathy (FEVR). In this study,...

Outcome of surgery for infantile exotropia after long-term follow-up of 4 years

The purpose of this study was to report long-term motor and sensory outcomes after unilateral lateral/medial rectus recession/resection (RR) in infantile constant exotropia. This was a retrospective review from 1995–2020 of 20 children (10 female, 10 male) with minimum 4-year...

Brexit, for richer, for poorer: prospects for post-withdrawal Britain

The people of the United Kingdom voted by 52% to 48% to leave the European Union (EU) in June 2016, a referendum decision intended by a slim majority to restore national self-determination and achieve what many believed to be a...

Applying for ophthalmology ST1 in 2026: What’s new?

Competition for ophthalmology ST1 has intensified steadily over recent cycles, rising from ~9:1 (2022) to ~10:1 (2023), ~14:1 (2024) and ~22:1 (2025) [1]. Against this background, applicants benefit from a structured approach: mapping achievements to portfolio domains early, identifying gaps...

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges

Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...

Glaucoma UK announces winners of the 2025 ‘Excellence in Glaucoma Care Award’

Glaucoma UK is delighted to announce the winners of this year's Excellence in Glaucoma Care Awards – Patrick (Paddy) Gunn from Manchester and Alex Gage Family Optometrists in Sheffield. This annual award celebrates individuals or teams who have made remarkable...

Dec/Jan Quiz 2014

History A 25-year-old West African male presents with oral candidiasis, generalised lymphadenopathy and a red nodule in the left upper eyelid. This is biopsied. See histology images. Figure 1. Figure 2. Figure 3. Questions 1. Describe Figure 1 (haematoxylin and...

A standardised strategy for uveitis etiological diagnosis

This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...