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Relationship between diabetic retinopathy and cerebrovascular reactivity changes

Cerebral micro-angiopathy caused by diabetes can manifest itself as an impairment in cerebrovascular reactivity. Transcranial doppler ultrasound (TCD) is a cost-effective and non-invasive way to measure the cerebrovascular reactivity. This study aimed to assess the relationship between the grade of...

Referral patterns and pathways for intracranial hypertension

The authors present a retrospective case review of individuals with suspected raised intracranial pressure (ICP) over a 12-month period a single tertiary neuro-ophthalmology centre. Cases were categorised into four groups based on examination by neuro-ophthalmology; 1) referred after identification of...

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Epidemiology of ocular cancer in Cali

The aim of this study was to describe the population trends of incidence and survival rates of ocular cancer in Cali, Columbia. Data was retrieved from the Registro Poblacion de Cancer de Cali (RPCC, i.e. Population Cancer Registry of Cali)...

Horizontal recti injection of botulinum toxin for treatment of infantile nystagmus

In this study the authors aimed to demonstrate the effect of botulinum toxin (BT) on the frequency of ocular oscillation in children with infantile nystagmus syndrome (INS). Botulinum toxin was administered with direct injection into the horizontal recti muscles using...

Treatment of anisometropia and strabismus amblyopia with syntonic phototherapy

Syntonic phototherapy is a non-invasive light therapy treatment using specific light colours, frequency and wavelength to improve body regulatory centres in the brain. It is proposed that red light increases cell membrane capacitance buildup of electrical charge before discharge that...

TowardPi Brings Next-Generation OCT/A to the UK

TowardPi, a fast-growing leader in ophthalmic imaging, has entered the UK market with its advanced swept-source OCT (SS-OCT) and OCT angiography (OCTA) systems. Distributed exclusively by Mainline Instruments, TowardPi is already well-established in Asia and is recognised for pioneering the...

What plane should be used for ultrasound measurement of the optic nerve sheath diameter?

This prospective observational study aimed to evaluate the differences between optic nerve sheath diameter (ONSD) between the patients’ two eyes and different ultrasound planes (transverse and sagittal). Participants were recruited over a two-year period from a single neurosurgical department. To...

Introducing: iGLEAMS-3

30 September (Colchester FirstSite) – 1 October (Colchester ICENI Centre)

Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis

A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.

An anterior segment lump: a diagnostic and treatment challenge

Case presentation A 50-year-old female presented to eye casualty with a lump on the left medial lower eyelid with associated redness and occasional bleeding. The lump was present for a few months with recent enlargement (Figure 1). Her past medical...

Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...