MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...
Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...
Although it’s autumn, it’s not too cold and the slight breeze blowing up from the sea does not make me regret leaving my jacket in clinic. It’s a strange site; hundreds of hospital staff standing on either side of the...
One of the great disasters of becoming a consultant ophthalmologist is the massive increase in emails that then occurs. Every time I open my inbox in work it seems complete luck whether there are 50 or 90 emails waiting avidly...
Introduction Myopia can be associated with any type of strabismus, but high myopia has increased frequency of esotropia and vertical heterotropia. The incidence and severity of the strabismus increases with the degree of myopia and age of the patient. Classification...
5 June 2023
| Rahila Bashir, Nick Astbury
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EYE - General
One sunny Thursday afternoon, in the spring of March 2023, I was invited to attend a zoom call with Nick Astbury, who works part-time at the International Centre for Eye Health at the London School of Hygiene & Tropical Medicine....
2 August 2024
| Andrew Blaikie, Chimgee Chuluunkhuu, Henry E Marealle, Frank Maliko, Dechen Wangmo
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EYE - General
In this three-part series (Click here for Part 1 and Part 2) Andrew Blaikie and his team explore the role and application of the Arclight Device in Imaging of the Eye. The Arclight Project aims to support and enhance the...
Ike (Iqbal) K Ahmed is a pioneering ophthalmologist from Canada, currently serving as Assistant Professor at the University of Toronto, and Clinical Assistant Professor at the University of Utah. He is also the Research Fellowship Director, Department of Ophthalmology, University...
The authors present a retrospective case series including all patients with microbial keratitis and ocular surface diseases (OSD), including dry eye, blepharitis, Stevens-Johnson syndrome and / or ocular cicatricial pemphigoid, over a five-year period between 2012 and 2016. A total...