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National dementia guidelines updated thanks to Moorfields-led initiative
The National Institute for Health and Care Excellence (NICE) has today updated its national dementia guidance to recommend that all patients newly diagnosed with dementia are offered an eye health assessment with an optometrist. Previously, patients diagnosed with dementia were...Student Ophthalmology Review Day: SORD
by Josephine A Bates, FY2 Doctor, North Devon District Hospital, Barnstaple, UK. Opening its doors to medical students across the country once again, the Royal College of Ophthalmologists hosted the Student Ophthalmology Review Day (SORD) with a fantastic turnout. Dr...
Preoperative RPE alterations in macular holes
This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...Gemini Untwined: treating craniopagus conjoined twins
The authors discuss the successful separation of craniopagus conjoined twins at Great Ormond Street Hospital and the role of the ophthalmologist in such cases. Craniopagus conjoined twins are extraordinarily rare, occurring in only one in 2.5 million births and representing...Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)
Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...
Esotropia Duane’s syndrome (DRS) surgery
The authors aimed to compare the safety and efficacy of augmented superior rectus transposition surgery with / without medial rectus (MR) recession versus MR recession along in the treatment of esotropic DRS. This was a prospective randomised trial of 20...
Partial recession surgery for small angle vertical strabismus
The objective of this study was to assess the results of partial recessions of the vertical rectus muscles in patients with diplopia and small angle vertical strabismus. This was a retrospective study of partial temporal or nasal recession from one...
Differences in strabismus surgery outcomes in preterm vs full-time birth infants
This study aimed to analyse motor and sensory outcomes of strabismus surgery in 70 preterm (group 1) and 242 full-term (group 2) infants. Group 1 mean gestational age and birth weight were 31.25 ±2.51 weeks and 1562.70 ±412.82g. Pre and...
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
New mouse model of diabetes mellitus
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...
