You searched for "macular"
Correlation between aqueous flare and macular microvascular status in diabetes mellitus
7 April 2021
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Aqueous flare, Diabetic retinopathy, Inflammation, Laser flare-cell meter, Microvascular injury, Optic coherence tomography angiography
The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...
OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema
1 December 2021
| Su Young
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EYE - Vitreo-Retinal
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Diabetic macular edema, aflibercept, optical coherence tomography, predictive, ranibizumab
This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....
OCT findings after strabismus surgery for macular, choroidal and nerve fibre thickness
This study used OCT to investigate the changes in the central macular thickness, subfoveal choroidal thickness (SFCT) and retinal nerve fibre layer (RNFL) after horizontal rectus surgery for patients with strabismus. This was a retrospective study and patients were grouped...Simulating the visual impairment symptoms of age-related macular degeneration in virtual reality
5 June 2023
| Cameron R M Wilson, Ian Underwood, Baljean Dhillon (Prof)
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EYE - Vitreo-Retinal
A new virtual reality application visually simulates age-related macular degeneration and demonstrates its progression over time including some Charles Bonnet syndrome hallucinations. Introduction Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries with the prevalence of...
More sensitive visual acuity test for age-related macular degeneration
1 October 2016
| Roger S Anderson (Prof), Nilpa Shah
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...
Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Optic neuritis, axonal degeneration, neurofilament protein, retina, tissue
Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...
The prevalence of macular cysts in patients with clinical cone-rod dystrophy determined by spectral domain optical coherence tomography
1 August 2014
| Huw Edward Oliphant
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EYE - Vitreo-Retinal
Cone-rod dystrophy is a progressive photoreceptor disorder which has multiple inheritance patterns. It is rare, with a prevalence of 1 in 40,000. Macular cysts are well recognised in other photoreceptor conditions such as retinitis pigments and choroideraemia, while they are...
Traumatic macular holes: reconstructive changes in foveal microstructures and visual predictor analysis, following surgical repair
5 April 2022
| Sofia Rokerya
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EYE - Vitreo-Retinal
The purpose of this paper was to investigate the reconstructive changes in foveal microstructures postoperatively and analyse the visual predictors in eyes with surgically closed traumatic macular holes (TMHs). This retrospective study analysed the data collected from 71 eyes of...
Treatment of diabetic macular edema in vitrectomised eyes – comparison of intravitreal dexamethasone implant and posterior subtenon triamcinolone injection
3 April 2023
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Dexamethasone implant, Diabetic macular edema, Pars plana vitrectomy, Posterior subtenon triamcinolone
This retrospective study was aimed to compare intravitreal dexamethasone implant and posterior subtenon triamcinolone injection (PSTA) in the treatment of diabetic macular edema (DME) in vitrectomised eyes. Sixty-four (48.12%) patients who had received PSTA and 69 (51.88%) patients who had...
Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders
3 February 2023
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Aflibercept, Anti-VEGF, Dexamethasone implant, Diabetic macular oedema, Persistent, Ranibizumab, Resistant
This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...
Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes
This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...Effectiveness and Safety of Dexamethasone implants for post surgical macular oedema including Irvine-gass syndrome
1 April 2018
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a retrospective, multicentre, uncontrolled, consecutive case series from Lyon, France between April 20111 to June 2014, with minimum of one year follow-up. The clinical features including the best corrected acuity (BCVA), central subfield macular thickness (CSMT) and intraocular...