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Practice Plus Group: CSR in primary care optometry
28 April 2025
Practice Plus Group Ophthalmology are delighted to offer a virtual accredited event for local referrers: ‘CSR in primary care optometry’Central serous retinopathy (CSR) is the fourth most common medical retinal condition which affects mainly patients of working age. It is...
Practice Plus Group: CSR in primary care optometry (1)
28 April 2025
Practice Plus Group Ophthalmology are delighted to offer a virtual accredited event for local referrers: ‘CSR in primary care optometry' Central serous retinopathy (CSR) is the fourth most common medical retinal condition which affects mainly patients of working age. It...
OCTA FAZ measurements in vein occlusion
1 February 2018
| Saruban Pasu
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EYE - Vitreo-Retinal
Previous studies have confirmed that foveal avascular zone (FAZ) enlargement is correlated with visual acuity impairment in patients with retinal vein occlusion (RVO). This current study aimed to evaluate the OCT angiography parameters: the area of FAZ, foveal and parafoveal...
The clinical spectrum of albinism
The authors sought to examine clinical correlates that may be related to foveal development in albinism with an aim to qualitatively describe the phenotype spectrum of albinism. Binocular best corrected visual acuity ranged from 20/20 to 20/80. Best corrected visual...MicroRNA inhibits corneal neovascularisation
1 August 2018
| Graham Wallace
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EYE - Cornea, EYE - General
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Biomechanical stress, Corneal epithelium, MicroRNA-204, Neovascularization, VEGF, VEGFR2
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
Corneal stroma modelling under hypoxic conditions
1 August 2018
| Graham Wallace
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EYE - Cornea, EYE - General
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Confocal fluorescence microscopy, Cornea, Corneal organ culture, Extracellular matrix, Stroma
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...
OCTA to measure surgical haemodynamic changes
This study used the optical coherence tomography angiography (OCTA) technique to evaluate possible haemodynamic changes after horizontal rectus muscle surgery in 32 eyes of 16 patients; nine male, seven female. Recession / resection surgery was undertaken for two horizontal rectus...OCTA to measure surgical hemodynamic changes
This study used the optical coherence tomography angiography (OCTA) technique to evaluate possible hemodynamic changes after horizontal rectus muscle surgery in 32 eyes of 16 patients; nine male, seven female. Recession / resection surgery was undertaken for two horizontal rectus...Sexually transmitted conjunctivitis – the REALLY sticky eye
Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...The ocular manifestations of COVID-19: an overview of current literature
Although respiratory symptoms are the most frequent manifestation of COVID-19, multi-organ involvement has been demonstrated, including ocular manifestations. The author investigates how the eye can be affected. The SARS-CoV-2 virus responsible for the COVID-19 pandemic has presented a significant public...Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)
3 February 2023
| Li Yen Goh
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EYE - General
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...
Assessing the effectiveness of undergraduate ophthalmic assessments in the UK: A literature review
2 June 2025
| Connor Henry-Blake, Elisabeth Baggus, Muhammed Jawad
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EYE - General
During 2008–2009, 300,000 patients presented to hospital emergency departments in the UK with eye conditions. This rose by nearly 200,000 over the next decade. As the population ages, the prevalence of eye disease increases [1,2]. However, the stake ophthalmology holds...