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Pathophysiology of diabetic macular oedema: why combination therapy may be better
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...The next wave of AI in ophthalmology: From screening to communication
Artificial intelligence (AI) is reshaping ophthalmology, moving from research laboratories into everyday clinical care [1]. With its strong reliance on imaging and pattern recognition, ophthalmology is uniquely positioned to benefit from AI innovations. These developments range from autonomous disease screening...
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...Leading sight loss charity reveals urgent need for change in attitudes towards blind mothers
Ahead of Mothers’ Day, leading sight loss charity the Royal National Institute of Blind People (RNIB) has released research that shows the barriers faced by mothers with sight loss during pregnancy and into their first years of motherhood. This research...In conversation with Robert Johnston
Robert Johnston. What is your current role with Medisoft? Clinical Director, i.e. I head up the analysis for and design of Medisoft’s ophthalmology electronic medical records (EMR) product. I don’t program: all coding is done by Medisoft’s team of computer...An interview with Rachel Morris: Clinician wellbeing and difficult conversations
In the last wellbeing supplement, I interviewed Robert Self, Vice President of the Association of Anaesthetists, and we discussed the resources that doctors can access when experiencing problems with their wellbeing. One of those that he recommended was the podcast...Ophthalmic mentors: In conversation with Professor Harminder Dua
In the first of a series of interviews with key figures in the world of ophthalmology, Eye News speaks to Professor Harminder Dua about the future of clinical academia, his recent College presidency and Dua’s Layer. Professor Harminder Dua is...Global health milestone as Pakistan becomes 19th country to eliminate blinding trachoma
Sightsavers commends Pakistan following the World Health Organization (WHO) announcement that it has become the nineteenth country to eliminate blinding trachoma as a public health problem. This phenomenal achievement means around 3.7 million people [1] in Pakistan are no longer...Enhancing glaucoma awareness and management in Nigeria – from grass roots to national policy development
This is the second in a series (see Part 1 here) of three articles about strengthening eye health services in Nigeria through collaboration with the LINKS and Networks run at the International Centre for Eye Health, LSHTM. This article highlights...Presumed DALK stromal graft rejection following Covid-19 infection
Case report A 45-year-old healthy male patient with a past ocular history of keratoconus and right deep-anterior lamellar keratoplasty (DALK) graft performed 10 months prior, presented to our eye casualty clinic with a two-day history of right photophobia and epiphora....
