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RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...

PD-1 and retinal ganglion cell death

Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...

Effectiveness and Safety of Dexamethasone implants for post surgical macular oedema including Irvine-gass syndrome

This is a retrospective, multicentre, uncontrolled, consecutive case series from Lyon, France between April 20111 to June 2014, with minimum of one year follow-up. The clinical features including the best corrected acuity (BCVA), central subfield macular thickness (CSMT) and intraocular...

Surgical outcomes in third nerve palsy

The authors of this article explore the factors associated with successful surgical outcomes in third nerve palsy, which is known to be difficult to treat. A number of case notes were reviewed for patients who underwent surgery or botulinum toxin...

Long-term retinal changes following unilateral retrobulbar optic neuritis

The aim of this study was to assess the longitudinal changes in retinal nerve fibre layer (RNFL) thickness after a first attack of optic neuritis and to investigate the impact of treatment on RNFL thinning at one year after the...

Postop improved fusion and stereopsis in IDEX

This study aimed to evaluate changes in binocular visual function in patients with different ages before and after surgery to explore the optimal timing of intermittent exotropia surgery. The study comprised 28 females and 25 males. Fifty-three patients were split...

Is an increased homocysteine level associated with greater risk of AMD?

Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...

ILM peeling in primary rhegmatogenous retinal detachment

This author retrospectively analysed the correlation between internal limiting membrane (ILM) peeling and the occurrence of a postoperative epiretinal membrane (ERM) in patients who underwent vitrectomy for rhegmatogenous retinal detachment (RD). There were 135 medical records investigated. Seventy patients underwent...

Intraocular surgical training – is there any inter-procedural transfer of skills?

Cataract surgery is the most commonly performed surgery during ophthalmology training. This study aims to investigate how experience in simulated cataract surgery impacts and transfers to the learning curves for novices in vitreoretinal surgery. Twelve ophthalmology residents without previous experience...

Binocular summation responses in strabismic amblyopia

A preliminary study was conducted to determine whether binocular summation (BS) in strabismic amblyopia is more decreased than in strabismus alone and whether strabismus surgery improves BS. The study included 15 strabismic amblyopes, 30 normal controls and 30 strabismic controls....

Results of surgery in a case of FMNS

The authors present the effects of the tenotomy and reattachment procedure on a patient with accommodative strabismus and fusion maldevelopment nystagmus syndrome (FMNS) who did not require strabismus correction. The ocular motility study of this patient allowed the opportunity to...

Childhood headaches

The goal of this study was to compare headache resolution in children receiving or not receiving refractive correction. The authors conducted a retrospective review of 158 patients: 78 male and 80 female aged three to twelve years (mean eight). Twenty-seven...