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MRI characteristics of NMO, MOG and MS-related ON

This review article examined differences of MRI appearances that can help clinicians assess and manage these important neuro-ophthalmic disorders. It also examined the role of optic nerve MRI as a prognostic indicator in acute optic neuritis (ON). The major findings...

Quiz Aug/Sep 2025

History A 78-year-old female presented with bilateral, painless, progressive blurring of vision over five years, photophobia and increasing glare. Her past medical history included a known diagnosis of monoclonal gammopathy of undetermined significance (MGUS). On examination, vision in the left...

An anterior segment lump: a diagnostic and treatment challenge

Case presentation A 50-year-old female presented to eye casualty with a lump on the left medial lower eyelid with associated redness and occasional bleeding. The lump was present for a few months with recent enlargement (Figure 1). Her past medical...

Updated Guidance for Professional Practice published by College of Optometrists

The College of Optometrists has today (11 December) published updated Guidance for Professional Practice for optometrists, including new sections.

Laser pointer maculopathy

The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...

Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review

Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...

RCOphth Back to Basics - Byte sized topics for all

The Royal College of Ophthalmologists Back to Basics - Byte sized topics for all

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

New Treatments in Noninfectious Uveitis

As a specialist registrar training in Aberdeen there were two important lessons I learned which have proved to be invaluable over the years for two very different reasons. The first lesson learned was to never underestimate the wind chill factor...

Aug/Sep 2014 Quiz 2

History A 27-year-old man presented to the emergency department with blurred vision and central scotoma in the right eye (RE) over the previous weeks. He had no relevant medical history and he was not on any current medication. However, he...

Aug/Sep 2015 Quiz 1

History A 60-year-old woman was referred to ophthalmology with a suspected left eye choroidal naevus. Visual acuity was unaffected in both eyes and she was asymptomatic. Ocular history and medical history were unremarkable. Questions Figure 1: Fundus photograph. 1. What...

Moorfields: Ocular emergencies level 1

Designed for optometrists, orthoptists, nurses and other allied ophthalmic health professionals, this module will deliver the knowledge and skills required for the examination, investigation, diagnosis, treatment, and management of patients who present in an ophthalmic emergency setting. Entry requirementsBSc (Hons)...